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Why Do Only Certain Brain Tumors Respond to Immunotherapy?
A new study has shown why tumors that have spread to the brain respond to immunotherapy while cancers that originate in the brain, like glioblastoma, do not.
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Statins May Lower Cancer Risk for Ulcerative Colitis Patients
Cholesterol-lowering statins might protect patients with ulcerative colitis from developing and dying from colorectal cancer. Statin treatment was also associated with a lower risk of death regardless of cause in patients with ulcerative colitis.
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Brain Tumor Gene Therapy Shows Early Promise in First-in-Human Trial
Combination drug and immunotherapy treatment can extend survival in patients with gliomas, a highly aggressive form of brain cancer, suggests a new Phase 1, first-in-human trial.
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Cancer Cells Can Survive Chemotherapy Using Cellular “Recycling”
Doxorubicin can induce oxidative stress in a cell’s endoplasmic reticulum (ER) and severe ER impairment in cardiomyocytes can lead to cardiac dysfunction. Researchers have now discovered a protective mechanism against drug-induced cardiotoxicity.
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Tumor Blood Flow Can Be Boosted by Antioxidants
Antioxidants neutralize free oxygen radicals and are commonly found in dietary supplements. However, according to new research, antioxidants like vitamin C and E induce the formation of new blood vessels by activating a protein called BACH1.
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Degrading a Key Cancer Protein Could Help Stop Tumor Growth
Overexpression of Lysine-specific histone demethylase 1A can drive the development of cancer. Scientists have now shown that degrading the entire protein leads to better results than short-circuiting the chemical reaction leading to overexpression.
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Cancer Drug “Envelope” Protects Against Heart-Damaging Side Effects
Researchers have developed a protein “envelope” that surrounds the cancer drug doxorubicin, both increasing its chances of being taken up by cancer cells and decreasing its toxic effects on lab-grown heart cells.
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Pancreatic Cancer Drug Targeting Scar-Like Tissue Shows Promise in Animal Models
A study has revealed a new Australian drug demonstrates potential for treating pancreatic cancer. The drug shows promise for treating pancreatic ductal adenocarcinoma, one of the most aggressive forms of pancreatic cancer.
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Kencur Ginger’s Anti-Cancer Effects Revealed
Osaka Metropolitan University scientists demonstrate the anti-cancer properties of Kencur ginger are caused by its bioactive compound, ethyl p-methoxycinnamate (EMC). In mice, this compound reduced cancer cell proliferation at low doses.
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Uncovering Why Some Breast Cancer Survivors Don’t Take Their Meds
Despite their promised benefits, 40% of breast cancer patients stop taking medication early. A study has found that interventions can increase medication adherence by nearly 1.5 times.
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