News

A new study suggests that prolonged exposure to low-dose radiation – such as for workers in the nuclear industry – is associated with an increased risk of death from cancer.

An immunotherapy drug combination could be an effective second-line therapy for patients with aggressive melanoma that is resistant to the widely used immunotherapy drugs known as PD-1 inhibitors.

Scientists have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal models.

A large-scale international collaboration has identified new genes associated with breast cancer that could eventually be included in tests to identify women at increased risk of the disease.

Researchers applied “genome graph” techniques developed to detect massive structural DNA changes that rearrange, copy, and delete huge sections of chromosomes.

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments. The compound nearly doubled survival.

New cancer drugs are being launched rapidly before their long-term effectiveness for patients can be evaluated. A new study suggests that there is still a lack of evidence for many new cancer drugs, even several years after their launch.

Researchers have used mathematical models and dynamic biomarkers to identify characteristics of metastatic cancer that are associated with better patient outcomes.

Deep analysis of the proteins that drive multiple cancer types reveals information that can’t be assessed by standard genome sequencing alone, and opens avenues for new therapies that block these driving mechanisms.

A newly developed, versatile and low-cost long-read RNA sequencing tool could accelerate the discovery of new diagnostics and treatments.