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Turning Cancer-causing Proteins Off
Biophysicists have used supercomputers to show how cell membranes control the shape, and consequently the function, of a major cancer-causing protein.
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FDA Approve First Drug for Rare, Aggressive Skin Cancer
Immunotherapy drug avelumab (Bavencio®) has been given the green light for some patients with Merkel cell carcinoma.
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Exploiting the Tumor Microenvironment to Enhance Cancer Treatment
Study finds that tumor blood vessels and the immune system influence each other’s functions, and propose that considering these bilateral effects in cancer therapy might improve outcomes.
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Giving Immunotherapies the Green Light to Attack
Preclinical study demonstrates the use of nanoparticles to improve the efficacy of immunotherapy drugs known as checkpoint inhibitors.
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Microfluidic Device Detects Circulating Plasma Cells
The microfluidic device could offer a less invasive way of diagnosing and monitoring multiple myeloma than current bone marrow biopsies.
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New Gene-Based Blood Test for Skin Cancer
The new blood tests take only 48 hours to complete, and reliably identify melanoma DNA in a patient's blood.
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Telomere Length Predicts Cancer Risk
The length of the telomere “caps” of DNA that protect the tips of chromosomes may predict cancer risk and be a potential target for future therapeutics.
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SMARCE1 Linked to Aggressive Early Stage Breast Cancer
Findings make it possible to distinguish poorly invasive tumors from those that will likely spread and metastasize.
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Screening the Dark Genome for Disease Genes
CRISPR-based system quickly screens non-coding genome for regulatory elements of disease genes.
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