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Novel Drug Combination Improves Outcomes in Patients With Early Breast Cancer

A study found when ribociclib, a targeted therapy drug, is added to hormone therapy there are a significant invasive disease-free survival benefit in patients with early hormone-receptor (HR) positive/HER2 negative breast cancer.
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Clinical Trial Shows Newly Approved Drug's Potential for Rare B-Cell Lymphoma

Results of a trial of pirtobrutinib highlight the drug’s impact and potential for pre-treated mantle cell lymphomas.
A figure from the scientific paper showing spatial metabolomics images of a mouse brain with a tumor.
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New Spatial Imaging Method Measures Flow of Nutrients in Tumors

New spatial tools measure how fast nutrients in tumors flow through different pathways, identifying pathways whose activities are uniquely elevated in brain cancer and offering clues for potential treatment strategies.
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Personalization May Improve Prostate Cancer Screening Accuracy

Prostate-specific antigen (PSA) levels are the main biomarker for prostate cancer, and new research has shown how accounting for genetic differences can make PSA screening for cancer more accurate.
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Study Provides New Information for Blood Cancer Treatment During Pregnancy

Fighting relapsed/refractory lymphoma during pregnancy requires critical decision-making from patients and providers, yet prior to this study, no data existed to inform these choices.
DNA damage in cells shown using a fluorescent microscope.
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Antioxidant Enzymes Repair DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.
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First-of-Its-Kind Platform Provides Resource for Childhood Cancer Research

A new research collaboration paves the way for new models to accelerate discoveries.
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Precancerous Growths in Colon Linked to Microbiome Changes

Understanding the link between the gut microbiome and polyp growth opens the door to potential screenings and treatments.
Diagram showing the response from metastatic lymph node targeted immune checkpoint blockade.
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New Cancer Immunotherapy Approach Improves Efficacy and Side Effects in Mice

Scientists have discovered a novel approach that improves the efficacy of immune checkpoint inhibitor cancer treatment and minimizes the associated side effects.
3D, computer-generated image of cancer cells.
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Two-Pronged Cell Therapy Targets Melanoma Spread to the Brain

A two-pronged stem cell therapy has been developed in a new study, which shows can suppress tumor growth and prolong survival in preclinical animal models.
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