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Molecular Marker Predicts Recurrence of Aggressive Brain Tumors
According to research, the loss of a single copy of CDKNA/B genes can significantly accelerate the recurrence of aggressive meningiomas.
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Iron-Dependent Cell Death Could Be Key to Liver Tumor Treatment
A new study has identified three substances that can fight tumour growth and reduce liver metastases.
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Non-Responders to Cancer Immunotherapy May Lack Vital Immune Cells
A specific subset of immune cells – CD5+ dendritic cells – might make the difference between a patient responding to immunotherapy, or not.
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Breakthrough for Creating “Next-Generation” Light-Activated Cancer Treatments
Researchers have engineered antibody fragments that work by forming a covalent bond with the target upon irradiation with UV light of a specific wavelength.
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New Approach Hits “Undruggable” Cancer Target
Researchers may have found success targeting STAT5, a protein that has been consigned to the “undruggable” category, with a new approach.
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Cell Movement Analysis by AI May Be Useful for Drug Discovery
Researchers have used artificial intelligence (AI) to track cell movement over time and space, in a method that could be helpful for the development of more effective cancer therapies.
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Blood Pressure Drug May Benefit Pancreatic Cancer Patients
The blood pressure drug losartan has been shown to reduce tumor invasion and immunosuppression in pancreatic cancer patients undergoing combination therapy treatment.
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Different Breast Cancer Risk Models May Misclassify Patients
According to research, breast cancer risk estimates for individual women differ depending on which risk assessment model is used, and women are likely receiving vastly different recommendations depending on the model used.
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Protein Key to Tumor Cell Metabolism and Immune Evasion Identified
Tumor cells can alter their metabolism, and in doing so, dampen the body's anti-cancer immune response. A research team has identified a potential target for therapies in the protein key to this metabolic shift.
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Reengineering of Cancer Drugs Increases Their Versatility
Researchers have discovered a way to further tap the therapeutic potential of proteolysis targeting chimeras (PROTACs), small molecules used in cancer treatment and other conditions.
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