Agena, Horizon to Launch iPLEX® Reference Standards
News Apr 15, 2016
Agena Bioscience (“Agena”) and Horizon Discovery Group plc (“Horizon”) have announced a Supply and Distribution agreement to launch iPLEX® reference standards for performance verification of oncology assays used on the MassARRAY® System. Under the partnership, Agena Bioscience will offer multiplexed sets of iPLEX-branded reference standards containing somatic variants in key oncogenic genes implicated in colon, lung, and skin cancers.
These standards will be made from cell lines precisely engineered using Horizon’s proprietary genome engineering platform, and will be provided at fixed and known allelic frequencies, thereby mimicking real patient tumors. The MassARRAY System enables rapid assay development for targeted and highly sensitive mutation analysis. Tens to hundreds of actionable genetic variants are easily tested.
However, robust assay performance requires upfront analytical verification and validation. These standards, available through Agena Bioscience, will be a valuable resource for laboratories to speed analytical validation and serve as ongoing positive controls, complementing laboratories’ evaluation of clinical research specimens.
“We are committed to accelerating the development and deployment of clinical research tests on the MassARRAY System,” commented Pete Dansky, CEO of Agena Bioscience. “This development of standards for Agena Bioscience by Horizon will provide a cost-effective, optimized resource for efficient test deployment.”
Dr. Paul Morrill, President, Products, Horizon Discovery Group commented: “Horizon’s Reference Standards continue to gain traction in an ever wider range of applications and are increasingly used to harmonize results across platforms. We are therefore pleased that Agena chose to work with Horizon to support high quality assay validation in a clinical research setting for this, our first commercial agreement for use on a mass spectrometry platform.”
Belief in Fake Causes of Cancer is RifeNews
Mistaken belief in mythical causes of cancer is rife according to new research. Researchers at University College London (UCL) and the University of Leeds surveyed 1,330 people in England and found that more than 40% wrongly thought that stress (43%) and food additives (42%) caused cancer.READ MORE
CRISPR Diagnostics Could Detect Any Disease on a Paper StripNews
A nucleic acid-detecting diagnostics platform that harnesses the gene editing technology CRISPR was announced today by the newly-launched Mammoth Biosciences, which says the technology could change how we diagnose disease.READ MORE
Comments | 0 ADD COMMENT
World Congress on Advanced Structural and Molecular Biology 2018
Aug 22 - Aug 23, 2018
Asia Pacific Congress on Probiotics, Prebiotics and Nutrition
Oct 15 - Oct 16, 2018