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Anti-Inflammatory Drug Inhibits Resistant Triple-Negative Breast Cancer Cells

News   May 19, 2021 | Original story from Impact Journals, LLC

 
Anti-Inflammatory Drug Inhibits Resistant Triple-Negative Breast Cancer Cells

SUM149-MA cells surviving a 6-MP treatment are sensitive to chemotherapeutic drugs. After a 32 days treatment with 2 μM 6-MP, surviving cells were allowed to recover in a drug-free medium for 33 days. Following this, cells were treated in parallel with 5 nM paclitaxel or 50 nM doxorubicin for 6 days and then allowed to recover and grow into colonies for 17 days before staining with crystal violet. Cells treated with DMSO solvent in parallel served as controls. DMSO treated control plates were stained after 6 days. The number of colonies, counted manually on full-size images, are shown on the top right of photographs of dishes. Representative cell cultures are shown. Credit: Anthony Lucci and Balraj Singh

 
 
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