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Cancer Cells’ “Self-eating” Could Be Novel Drug Target

News   Jul 02, 2019 | Original story from Cold Spring Harbor Laboratory (CSHL)

 
Cancer Cells’ “Self-eating” Could Be Novel Drug Target

Evidence of activity involving the NIX protein (brown staining) is seen in common precursor lesions (PanIN) for pancreatic cancer. NIX activity escalates in full pancreatic ductal adenocarcinoma (PDAC), the most common of pancreas cancers. NIX is directly responsible for triggering mitophagy, or "self eating" of mitochondria. Credit: Tuveson lab/CSHL

 
 
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