We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

CRISPR Enhances Cancer Immunotherapy Helping Protect T-Cells Against Friendly Fire

News   Mar 07, 2018 | Original story from Washington University School of Medicine in St. Louis

 
CRISPR Enhances Cancer Immunotherapy Helping Protect T-Cells Against Friendly Fire

Scientists at Washington University School of Medicine in St. Louis now have used the gene-editing technology CRISPR to engineer human T cells that can attack human T cell cancers. They also engineered the T cells to eliminate a potentially dangerous side effect called graft-versus-host disease, where the therapeutic T cells that kill the cancer also attack the patient's organs. John DiPersio, MD, PhD, (right) leads a team developing an "off-the-shelf" CAR-T immunotherapy for hard-to-treat T cell cancers. A new study evaluates the approach in mice with human T cell acute lymphoblastic leukemia. Shown is DiPersio working with co-author Armin Ghobadi, MD, in the lab. Credit: Huy Mach

 
 
 

RELATED ARTICLES

Analytical Tool Predicts Disease-Causing Genes

News

Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers that has developed a new analytical tool to effectively and efficiently predict such candidate genes.

READ MORE

Gene Regulator May Contribute to Protein Pileup in Exfoliation Glaucoma

News

Researchers are seeking factors that contribute to protein pileup in exfoliation glaucoma

READ MORE

Single Gene Change in Gut Bacteria Alters Host Metabolism

News

Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice. The research provides an important step towards understanding how the microbiome – the bacteria that live in our body – affects metabolism.

READ MORE

 

Like what you just read? You can find similar content on the communities below.

Biopharma Genomics Research Immunology & Microbiology

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE