We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

CRISPR Enhances Cancer Immunotherapy Helping Protect T-Cells Against Friendly Fire

News   Mar 07, 2018 | Original story from Washington University School of Medicine in St. Louis

 
CRISPR Enhances Cancer Immunotherapy Helping Protect T-Cells Against Friendly Fire

Scientists at Washington University School of Medicine in St. Louis now have used the gene-editing technology CRISPR to engineer human T cells that can attack human T cell cancers. They also engineered the T cells to eliminate a potentially dangerous side effect called graft-versus-host disease, where the therapeutic T cells that kill the cancer also attack the patient's organs. John DiPersio, MD, PhD, (right) leads a team developing an "off-the-shelf" CAR-T immunotherapy for hard-to-treat T cell cancers. A new study evaluates the approach in mice with human T cell acute lymphoblastic leukemia. Shown is DiPersio working with co-author Armin Ghobadi, MD, in the lab. Credit: Huy Mach

 
 
 

RELATED ARTICLES

Revival of 50,000-Year-Old Gene Reveals How Deadliest Malaria Parasite Jumped from Gorillas to Humans

News

In a study published today in PLOS Biology, researchers from the Wellcome Sanger Institute and the University of Montpellier have reconstructed a ~50,000-year-old gene sequence acquired by the ancestor of Plasmodium falciparum. The acquisition of the gene sequence enabled the parasite to infect human red blood cells.

READ MORE

Microbiome Is Shaped by Genetic Differences in the Immune System

News

Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research by scientists at the University of Chicago.

READ MORE

How To Tame Your Microbes

News

Scientists have found some evidence that mucus is not just a physical barrier that traps bacteria and viruses, but it can also disarm pathogens and prevent them from causing infections.

READ MORE

 

Like what you just read? You can find similar content on the communities below.

Biopharma Genomics Research Immunology & Microbiology

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE