Enamine, EMBL Partner on Cancer Drug Discovery Research
Enamine and the European Molecular Biology Laboratory (EMBL) have agreed to establish a collaboration whereby Enamine provides library synthesis, medicinal chemistry and biological services for the discovery and development of novel small molecules against EMBL’s proprietary anti-cancer targets. The collaboration involves the deployment of a team of Full Time Equivalent (FTE) medicinal chemists at Enamine. This team will focus on the project’s multiple objectives towards creating new cancer therapeutics with novel modes of action.
Joe Lewis, Head of Chemical Biology Core Facility at EMBL commented: “We have been working with Enamine for several years, primarily to enhance the chemical space of our internal screening library. We realized quickly that their 2 million plus compound collection provides quality compounds allowing an increase in the chemical diversity of our screening deck. When we decided to outsource our important medicinal chemistry discovery program in Europe, Enamine was the obvious choice. We are convinced that the company best complements and enhances our core expertise in the interdisciplinary field of chemical biology and drug development.”
David Will, Head of Medicinal Chemistry at EMBL added: “This collaboration with Enamine will be pivotal for the success of our project for identifying targets from phenotypic screens and synthesizing and triaging new patentable preclinical compounds. Their agility and flexibility with access to the world’s largest collection of building blocks in stock at Enamine and integration of chemistry with a comprehensive biology service portfolio perfectly fit our goal of nominating a preclinical development candidate by 2018.”
“Our collaboration with EMBL illustrates our established engagement with non-profit academic research institutions and disease foundations in their search for strong and committed partners in the most challenging discovery research projects. We look forward to our continued successful work with EMBL”, concluded Michael Bossert, Head Strategic Alliances at Enamine.
This article has been republished from materials provided by Enamine. Note: material may have been edited for length and content. For further information, please contact the cited source.
HIV Envelope Trimer Immunization Approach OptimizedNews
Optimized immunizations reliably elicit protective antibodies in preclinical study, marking an important milestone on the way to an effective HIV vaccine.READ MORE
BMS, QIAGEN Partner to Develop Gene Expression Profiles for Immuno-OncologyNews
QIAGEN and Bristol-Myers Squibb intend to develop GEPs for several Bristol-Myers Squibb I-O molecules under the initial agreement.READ MORE
Fast Simple Method to Make and Modify Pyrimidine Nucleoside AnaloguesNews
New simple method enables modification of pyrimidine nucleosides, including AZT (zidovudine).READ MORE
Comments | 0 ADD COMMENT
Outsourcing in Clinical Trials Southern California
Sep 27 - Sep 28, 2017