We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
First Global Guidance for Preventing Cervical Cancer
News

First Global Guidance for Preventing Cervical Cancer

First Global Guidance for Preventing Cervical Cancer
News

First Global Guidance for Preventing Cervical Cancer

Credit: Pan American Health Organization PAHO flickr feed
Read time:
 

Want a FREE PDF version of This News Story?

Complete the form below and we will email you a PDF version of "First Global Guidance for Preventing Cervical Cancer"

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

The American Society of Clinical Oncology (ASCO) today issued a clinical practice guideline on human papillomavirus (HPV) vaccination for the prevention of cervical cancer. This is the first guideline on primary prevention of cervical cancer that is tailored to multiple regions of the world with different levels of socio-economic and structural resource settings, offering evidence-based guidance to health care providers worldwide. 


The guideline includes specific recommendations according to four levels of resource settings: basic, limited, enhanced and maximal. The levels pertain to financial resources of a country or region, as well as the development of its health system - including personnel, infrastructure and access to services. The guideline complements ASCO's two other global, resource-stratified guidelines on cervical cancer, also stratified to these four levels of resources.


Key guideline recommendations:


• In all environments and independent of the resource settings, two doses of human papillomavirus vaccine are recommended for girls ages 9 to 14 years, with an interval of at least 6 months and up to 12 to 15 months between doses. 


• Girls who are HIV positive should receive three doses. 


For maximal and enhanced resource settings: 


  • If girls are 15 years or older and have received their first dose before age 15, they may complete the two-dose series; 


  • If they have not received the first dose before age 15, they should receive three doses; 


  • In both scenarios vaccination may be given through age 26 years. 


• For limited and basic resource settings: if sufficient resources remain after vaccinating girls 9 to 14 years, girls who received one dose may receive additional doses between ages 15 and 26 years.


• Vaccination of boys: in all settings, boys may be vaccinated, if there is at least a 50% coverage in priority female target population, sufficient resources, and such vaccination is cost effective.


Cervical cancer is the fourth most common cancer among women worldwide, with less developed regions suffering a disproportionate burden from the disease. In fact, 85% of cervical cancer diagnoses and 87% of cervical cancer deaths occur in less developed regions, including parts of Africa and Latin America.


"Because resource availability varies widely, both among and within countries, we need to adjust strategies to improve access to HPV vaccination everywhere," said Silvia de Sanjosé, MD, PhD, co-chair of the Expert Panel that developed the guideline and head of the Cancer Epidemiology Research Program at Institut Català d'Oncologia in Barcelona, Spain. "This guideline is unique in offering cervical cancer vaccination recommendations that can be adapted to different resource levels and we expect it to have a major impact on the global health community." 


HPV infection causes virtually all cervical cancers in the world. Although it may also lead to genital warts and certain other cancers, cervical cancer is by far the most common severe condition related to HPV infection. Unlike other existing HPV vaccination guidelines, ASCO's guideline focuses on the use of HPV vaccination specifically for the prevention of cervical cancer. 


"Although HPV vaccine has been around for more than a decade, the uptake of the vaccine has been less than ideal in many places, including in high-resource countries such as the United States," said Silvina Arrossi, PhD, co-chair of the Expert Panel that developed the guideline and an official and researcher at the Instituto Nacional del Cancer in Buenos Aires, Argentina. "As an organization of cancer doctors, ASCO continues to endorse HPV vaccination programs and efforts to help spare more women around the world from this very difficult cancer."


This article has been republished from materials provided by American Society of Clinical Oncology. Note: material may have been edited for length and content. For further information, please contact the cited source.

Reference

Silvina Arrossi, Sarah Temin, Suzanne Garland, Linda O’Neal Eckert, Neerja Bhatla, Xavier Castellsagué, Sharifa Ezat Alkaff, Tamika Felder, Doudja Hammouda, Ryo Konno, Gilberto Lopes, Emmanuel Mugisha, Rául Murillo, Isabel C. Scarinci, Margaret Stanley, Vivien Tsu, Cosette M. Wheeler, Isaac Folorunso Adewole, Silvia de Sanjosé. Primary Prevention of Cervical Cancer: American Society of Clinical Oncology Resource-Stratified Guideline. Journal of Global Oncology, 2017; JGO.2016.008151 DOI: 10.1200/JGO.2016.008151
Advertisement