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New Details About Protein Binding Could Lead to Better Drugs

News   Nov 24, 2020 | Original story from Rice University

 
New Details About Protein Binding Could Lead to Better Drugs

Atom-scale models by Rice University scientists based on those used to predict how proteins fold show a strong correlation between minimally frustrated binding sites and drug specificity. The funnel, a visual representation of the protein's energy landscape as it folds, helps locate those frustrated sites. Such models could lead to better-designed drugs with fewer side effects. Credit: Mingchen Chen/Rice University

 
 
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