Ubiquitous and Influential

News   Feb 15, 2017 | Original story from Julius-Maximilians-Universität Würzburg

 
Ubiquitous and Influential

Metaphorical representation of the regulatory mechanism of the ubiquitin ligase HUWE1. The dimer form of HUWE1, as mediated by the molecular “thumb” and “pointer” regions, is inactive. In contrast, single molecules of HUWE1 in the active form assemble ubiquitin chains - through yet unknown mechanisms. (Graphic: Katharina Beer)

 
 
 

RELATED ARTICLES

Cells Missing Nuclei Struggle to Move in 3D Environments

News

University of North Carolina Lineberger Comprehensive Cancer Center researchers have revealed new details of how the physical properties of the nucleus influence how cells can move around different environments.

READ MORE

Cancer Stem Cell Survival is Controlled by Hedgehog Signaling Proteins

News

Research reveals that cancer stem cell survival is controlled by a specific feature of the Hedgehog signaling pathway (SHH-PTCH1), which allows cells to respond to external signals in addition to inhibiting stem cell differentiation.

READ MORE

Watch: Could Digital Microfluidics Revolutionise Experimentation?

News

Technology using 'programmable droplets' could enable automated research on a grand scale.

READ MORE

 

Comments | 0 ADD COMMENT

Like what you just read? You can find similar content on the communities below.

Drug Discovery Informatics & Automation Proteomics & Metabolomics

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE