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Latest Posters
Change in pattern of secondary malignancies following Kaposi's sarcoma in the era of anti-retroviral therapy
Poster

Change in pattern of secondary malignancies following Kaposi's sarcoma in the era of anti-retroviral therapy

This study hypothesis is that the secondary cancers that develop in patients with KS have changed.
Pharmacological Ascorbic Acid and Hyperbaric Oxygen Therapy Target Tumor Cell Metabolism via an Oxidative Stress Mechanism
Poster

Pharmacological Ascorbic Acid and Hyperbaric Oxygen Therapy Target Tumor Cell Metabolism via an Oxidative Stress Mechanism

This data indicates that AA exhibits anti-cancer effects in vitro through an OxS mechanism and that HBOT can enhance this therapeutic effect.
An Antitumor Antibody Response to Attenuate Metastatic Melanoma in a Murine Model
Poster

An Antitumor Antibody Response to Attenuate Metastatic Melanoma in a Murine Model

These preliminary results show antitumor activity of adoptive cell transfer of MHC class mismatched CD4(+) T-cells. The finding of reduced numbers of pulmonary metastases correlates with increased serum anti-OVA IgG and increased germinal center development in the spleen.
Activation of PTEN lipid phosphatase function in lung cancer
Poster

Activation of PTEN lipid phosphatase function in lung cancer

We have discovered novel small molecule compounds that directly induce PTEN function and antagonize PI3K/AKT pathway activity in lung cancer cells.
Isolated Limb Infusion as a Limb Salvage Strategy for Locally Advanced Extremity Sarcoma
Poster

Isolated Limb Infusion as a Limb Salvage Strategy for Locally Advanced Extremity Sarcoma

We review perioperative and oncological outcomes and compare survival between ILI and amputation.
Comparison of the Biological Effects of Long-Term Exposure of Human Bronchial Epithelial Cells to Total Particulate Matter from 3R4F Cigarette Smoke or Aerosol from the Candidate Modified Risk Tobacco Product (cMRTP) THS2.2
Poster

Comparison of the Biological Effects of Long-Term Exposure of Human Bronchial Epithelial Cells to Total Particulate Matter from 3R4F Cigarette Smoke or Aerosol from the Candidate Modified Risk Tobacco Product (cMRTP) THS2.2

We mimicked chronic exposure in smokers’ airways by continuously exposing BEAS-2B cells to TPM from 3R4F cigarette smoke or aerosol of the Tobacco Heating System 2.2 (THS2.2), a cMRTP, for 12 weeks.
Quantitative Cell-based Bioassays for Individual and Combination Immune Checkpoint Immunotherapy Targets
Poster

Quantitative Cell-based Bioassays for Individual and Combination Immune Checkpoint Immunotherapy Targets

The human immune system is comprised of a complex network of immune checkpoint receptors that are promising new immunotherapy targets for the treatment of a variety of diseases including cancer and autoimmune-mediated disorders.
Inecalcitol Stimulates CD38 Expression in Multiple Myeloma and Acute Myeloid Leukemia Cell Lines
Poster

Inecalcitol Stimulates CD38 Expression in Multiple Myeloma and Acute Myeloid Leukemia Cell Lines

Inecalcitol is a vitamin D receptor agonist currently in Phase II clinical trial in AML (acute myeloid leukemia). Inecalcitol increases the expression of CD38 at the surface of 5 multiple myeloma cell lines; therefore, inecalcitol could potentiate the clinical response of MM patients to a therapeutic anti-CD38 antibody
Inecalcitol induces the expression of the CD38 antigen at the surface of 4 AML cell lines; thus, inecalcitol could render AML patients sensitive to a therapeutic anti-CD38.
Functional Analysis of RAD51B and RAD23B SNPs using Circular Chromosome Conformation Capture (4C) in Human Prostate Cell Lines
Poster

Functional Analysis of RAD51B and RAD23B SNPs using Circular Chromosome Conformation Capture (4C) in Human Prostate Cell Lines

The aim of this study is to understand the mechanism behind the association between single nucleotide polymorphisms (SNPs), lying in non-coding regions near or within RAD51B and RAD23B, and prostate cancer risk by analysing their interactions with the whole genome using Circular Chromosome Conformation Capture (4C).
BAP1 Immunohistochemistry and p16 FISH in the Diagnosis of Malignant Peritoneal Mesothelioma
Poster

BAP1 Immunohistochemistry and p16 FISH in the Diagnosis of Malignant Peritoneal Mesothelioma

In order to differentiate peritoneal malignant mesothelioma (PMM) from primary peritoneal serous carcinoma (PPSC) and reactive mesothelial hyperplasia (RMH), we used immunohistochemistry to examine for BAP1, and FISH to examine for homozygous deletion of p16.

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