Polymer Microarrays for Biomaterial Development
The application of polymer microarrays in the discovery of biocompatible and bioactive substrates. Progress towards biomaterial development for the treatment of SIRS (systemic inflammatory response syndrome), and improving cervical cytology.
Knockdown of Long Noncoding RNAs in Breast Cancer
RNAi global collaboration study using Lincode siRNA in a primary screen of tumor and nontumor breast cell lines. Hundreds of lncRNAs are found to affect viability and cell morphology of breast cancer. Presented at Keystone Symposia on Long Noncoding RNAs: From Evolution to Function, Mar 15 - Mar 20, 2015.
Targeting Cancer Stem Cell-Related miRNAs for Prostate Cancer Therapy
The poster focuses on the pivotal function of miRNAs in tumorigenesis by regulation of self renewal and apoptosis via cancer stem cell signalling pathways with special focus on their regulation of Epithelial to Mesenchymal transition in metastatic prostate cancer.
A Multiplexed Amplicon Sequencing Technology for FFPE and Circulating, Cell-free DNA
A novel amplicon approach allowing for hundreds of amplicons to be multiplexed in a single tube with a two workflow from sample to sequencer.
Rapid Detection of Somatic Mutations in Cancer Genes
Rapid higly sensitive detection of tumor gene mutations in DNA derived from FFPE or plasma samples can be achieved with QClamp PCR technology.
Expression of Wnt5a in Urothelial Carcinoma as a Potential Prognostic Marker
Our results support the previous studies that suggest Wnt5a plays a pathological role in urothelial carcinoma.
TFAP2B is Associated with WNT/ß-catenin Pathway in Luminal Breast Cancer
Here we aimed to investigate which molecular mechanisms are associated with TFAP2B expression in luminal breast cancer.
Transcription Factors to Classify Tumor Types and Subtypes
Here we introduce the use of the unsupervised approach to identify transcription factors (TFs) that are specific for different tumor types.
Non-disruptively Count and Quantify Fluorescent iPS Colonies During Secondary Reprogramming: 7 min per 6-well Plate, Dual-fluorescence Whole Well Imaging Cytometry
Nexcelom’s Celigo imaging cytometer has been applied to provide automated, rapid assessment of iPS reprogramming.
Expression Profiling of Circulating Tumor Cells: a Prognostic and Predictive Biomarker in Cancer.
We show non-responders to treatment among breast cancer patients can be identified by expression profiling of circulating tumor cells