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Discover Live Cell Analysis at AACR 2017
Product News

Discover Live Cell Analysis at AACR 2017

Discover Live Cell Analysis at AACR 2017
Product News

Discover Live Cell Analysis at AACR 2017

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The IncuCyte® live-cell analysis platform from Essen BioScience will be showcased at the upcoming AACR conference, booth #1365.

A variety of applications will be highlighted at the booth and poster sessions across a variety of research and therapeutic areas including oncology, immuno-oncology, immunology, neuroscience and stem cell biology.  

The IncuCyte® system, placed directly in a standard incubator, automatically collects and analyzes images throughout the course of an experiment while cells remain unperturbed in a physiologically relevant environment. The platform provides researchers with the ability to gain new insights and understanding into biological processes via real-time, quantitative analysis of live cells.  

Poster Presentations

CD47 antibody-induced engulfment of human T cell leukemia cells by bone marrow-derived macrophages

CD47 is a trans-membrane “don’t eat me” signaling protein that enables tumor cells to evade clearance by phagocytes. Blocking CD47 allows phagocytes to identify and clear tumor cells and is a promising new approach for immunotherapy.  The poster will describe a model system for quantitative functional analysis and derivation of mechanistic insights into CD47 modulators as cancer therapeutics. 

Session date and time:  Monday, April 3, 1-5pm 

Location:  Poster section 26

A novel continuous live-cell assays for immune cell activation and killing of blood cell cancers 

Novel high throughput live-cell image-based assays for immune cell activation and killing of target cells enable screening for new treatments for blood cell cancers.  The assays allow non-invasive continuous measurement of proliferation, activation, clustering and immune-cell killing of non-adherent tumor cells at industrial scale. Unlike flow cytometry, this approach follows the full time-course of the biology without perturbing the cells and allows cell-cell interactions to be visualized. These assays are amenable to testing new therapeutic antibodies, small molecules and CAR-T approaches.

Session date and time:  Tuesday, April 4, 1-5pm 

Location:  Poster section 1