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New Nucleic Acid and Protein Purification System Helps Ensure Efficient, Reliable Purification

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Low and medium-throughput laboratories now have an alternative to manual processes and spin-column methods for nucleic acid purification, thanks to a new automated system. 

The Thermo Scientific KingFisher Duo Prime nucleic acid and protein purification system will debut at the American Association for Cancer Research (AACR) Annual Meeting 2015, booths 1501 and 1701 at the Pennsylvania Convention Center, April 18-22.

Designed for research labs and small biotech firms looking to simplify DNA, RNA and protein purification processes, the new KingFisher Duo Prime system builds upon the utility of the existing KingFisher Duo system to help improve reproducibility and deliver high quality samples with less time and effort than traditional manual methods. With the KingFisher Duo, isolating DNA from 12 blood samples takes as little as 53 minutes and only requires a mere 15 minutes of hands-on time, compared to manual spin-column methods, which take up to 90 minutes of hands-on time.

“Thermo Fisher Scientific continues to advance the functionality of its laboratory nucleic acid purification systems with the launch of the Thermo Scientific KingFisher Duo Prime system,” said Hanna Grano-Fabritius, business director, Sample Preparation and Analysis, Thermo Fisher Scientific. “With the KingFisher Duo Prime system, researchers can achieve high quality samples while streamlining purification efforts.”

Thermo Scientific KingFisher systems are designed to isolate DNA, RNA and proteins from a variety of starting materials, including cell-free body fluids, blood, bacteria, cell cultures, tissue and plant samples. Low-to medium-throughput laboratories typically rely on manual processes to purify these samples. Manual purification, however, is a lengthy process involving multiple hands-on steps that can introduce the risk of human error and sample degradation. 

Additional product features include:

• Advanced Functionality: Built-in UV lamp delivers easy and effective decontamination; and bar-code reader allows users to track samples directly in the internal software.

• Flexibility: Open platform allows researchers to optimize their workflow. Thermo Scientific KingFisher Pure reagent kits can be used for a complete, easy-to-use solution, while Thermo Scientific BindIt software enables users to make modifications and choose their own reagents.

• Reproducibility: Automated magnetic bead technology, included in all KingFisher systems, is designed to enable reproducibility of each assay run from researcher to researcher and day to day.

• Improved Usability: Additional language options make the system easier to operate for researchers around the globe. The new elution strip cap allows users to store their purified samples until they are ready to proceed with downstream analysis.