Growth Factors for the Culture of Lung and Digestive System Organoids

Generating robust organoids for the lung and gastrointestinal system to recapitulate the complex organ environment remains challenging. Quality growth factors (GFs), such as EGF, FGFs, Noggin, BMP, and RSPO1, are essential in this process. FGF10, HGF, and KGF/FGF7 have been shown to synergistically promote the formation of bronchioalveolar and alveolar organoids. FGF2 and IGF-1 also enhance intestinal organoid plating.

Sino Biological has a strong line of products for these growth factors and their corresponding receptors and activators, such as FGFR1, FGFR2, c-MET, HGFAC, and BMPR2 to support the research and development of organoid cultures and different diseases that these molecules are involved in.