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Cytokines are secreted immunomodulatory molecules that play an essential role in cell communication and immune reactions. Cytokines are produced throughout the body by cells of diverse embryological origins. Cytokines are defined based on their presumed function, cell of secretion, or target of action. For example, interleukins (ILs) are secreted by leukocytes and can affect the cellular responses of leukocytes.
Some cytokines, such as GM-CSF, IFN gamma (IFNγ), and IL-21, have been considered ideal targets for antitumor therapies and are being evaluated clinically. In addition to single-agent treatment, cytokines may be used with other immunomodulatory drugs, such as adoptive cell therapy, cancer vaccines, checkpoint inhibitors (anti-CTLA-4 or anti-PD-1/PD-L1), and cancer-directed monoclonal antibodies.
Sino Biological has launched a comprehensive collection of high-quality bioreagents to support the study and application of cytokines.
Sino Biological is an international reagent supplier and contract research service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced with a stringent quality management system, and include unique bioreagents addressing areas such as cell therapy, stem cell, and infectious disease research. For example, Sino Biological has a wealth of viral antigens (Provir®) and corresponding antibodies, with one of the world’s Extensive collections. Sino Biological is also a well-recognized, qualified source of recombinant cytokines and high-quality GMP-grade cytokines. In addition, Sino Biological offers contract research production services for the custom development of full length, bioactive proteins and high-affinity antibodies, along with other services. To learn more about Sino Biological visit www.sinobiological.com, follow us on LinkedIn or @SinoInc on Twitter.
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