Cell Signaling – News and Features

News
Heart Disease Drug Could Be Repurposed To Treat Growth Disorders
New research has revealed that a type of drug commonly used to treat heart disease, asthma and thrombosis, also stimulates bone growth – suggesting that these drugs could be repurposed for treating skeletal growth disorders.

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PGE2 Treatment Restores Muscle Stem Cell Function in Aged Mice
Researchers have demonstrated the effectiveness of treating aged mice with a naturally occurring lipid, Prostaglandin E2 (PGE2), which improved muscle regeneration and strength in older animals.

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Disrupting VIPR2 Could Halt Breast Cancer Progression
Researchers have elucidated at least one mechanism of breast cancer cell proliferation and migration. With the discovery, they may have also uncovered how short chains of protein building blocks could serve as a novel anticancer drug.

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New Regulator of Ovulation Identified
Researchers have discovered a new cell signaling pathway involved in ovulation, a potential target for future research on infertility, contraception and ovarian disease.

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AI Model Detects More Than 170 Types of Cancer
Researchers at Charité - Universitätsmedizin Berlin look for new cancer diagnostic procedures. The result is an AI model that makes use of the specific characteristics in the genetic material of tumors.

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How Do Cells Allocate Space for Organoid Growth?
Researchers have identified how cells pattern themselves to allocate space for organoid growth as conditions change.

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Ancient Gene Controls Synchronized Growth of Brain and Skull
MN1, a gene originally associated with brain tumors, evolved hundreds of millions of years ago to control brain and skull development.

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Metabolic Dysregulation Caused by High-Fat Diet Mapped
Researchers have mapped metabolic enzyme dysregulation in cells following a high-fat diet, associating these changes with weight gain.

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How Herpes Proteins Could Reinforce Cancer Immunotherapy
University of Michigan researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival.

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Exploring TRIO Gene’s Role in Autism and Schizophrenia
Researchers introduced three TRIO gene variants into mice, showing how each mutation led to brain size reduction and altered behavior, with differences in neuronal signaling via Rac1 activity.
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