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Cell Signaling – News and Features

An anatomical model of a human heart.
News

Heart Disease Drug Could Be Repurposed To Treat Growth Disorders

New research has revealed that a type of drug commonly used to treat heart disease, asthma and thrombosis, also stimulates bone growth – suggesting that these drugs could be repurposed for treating skeletal growth disorders.
Microscopic florescent image of muscle stem cells at different stages making muscle.
News

PGE2 Treatment Restores Muscle Stem Cell Function in Aged Mice

Researchers have demonstrated the effectiveness of treating aged mice with a naturally occurring lipid, Prostaglandin E2 (PGE2), which improved muscle regeneration and strength in older animals.
Cancer cell being targeted to be destroyed.
News

Disrupting VIPR2 Could Halt Breast Cancer Progression

Researchers have elucidated at least one mechanism of breast cancer cell proliferation and migration. With the discovery, they may have also uncovered how short chains of protein building blocks could serve as a novel anticancer drug.
A cell with a transparent membrane, revealing a blue center.
News

New Regulator of Ovulation Identified

Researchers have discovered a new cell signaling pathway involved in ovulation, a potential target for future research on infertility, contraception and ovarian disease.
Digital icons with person on laptop in background, indicating use of AI in medicine.
News

AI Model Detects More Than 170 Types of Cancer

Researchers at Charité - Universitätsmedizin Berlin look for new cancer diagnostic procedures. The result is an AI model that makes use of the specific characteristics in the genetic material of tumors.
A cell with its organelles mapped.
News

How Do Cells Allocate Space for Organoid Growth?

Researchers have identified how cells pattern themselves to allocate space for organoid growth as conditions change.
A person points at a scan of the brain.
News

Ancient Gene Controls Synchronized Growth of Brain and Skull

MN1, a gene originally associated with brain tumors, evolved hundreds of millions of years ago to control brain and skull development.
Flat-lay photography of fatty foods, including pizza, burgers, schnitzel and fries.
News

Metabolic Dysregulation Caused by High-Fat Diet Mapped

Researchers have mapped metabolic enzyme dysregulation in cells following a high-fat diet, associating these changes with weight gain.
White blood cells attacking cancer cell, illustrating immunotherapy.
News

How Herpes Proteins Could Reinforce Cancer Immunotherapy

University of Michigan researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival.
Glowing network of interconnected neurons transmitting electrical signals in the brain.
News

Exploring TRIO Gene’s Role in Autism and Schizophrenia

Researchers introduced three TRIO gene variants into mice, showing how each mutation led to brain size reduction and altered behavior, with differences in neuronal signaling via Rac1 activity.
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