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Light Microscopy – News and Features

Fluorescence microscopy images of vpCell Pools.

Novel Method Allows Simultaneous Fluorescent Labelling of Many Proteins

Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge. A research group has now overcome this hurdle: With a novel method.
A bacteriophage with bacteria in the background.

Researchers Discover Mechanism Behind How Phages Disarm Pathogenic Bacteria

Researchers have uncovered how bacteriophages disarm antibiotic-resistant bacteria, opening doors to the possibility of new treatment methods.

Shaping Cells With Light

Imagine switching on a light and being able to understand and control the inner dynamics of a cell. By shining lights of different colors on replicates of cells, researchers altered the interactions between cellular elements.
Histology of ovaries from healthy mice vs. mice without Usp7 gene.

Researchers Uncover Protein Networks in Female Mouse Reproduction

Scientists have found that while a protein called FOXL2 plays a role in embryonic development, it regulates the activity of many more genes after birth.
A graphic of a cell membrane, showing proteins and lipids embedded in the lipid bilayer.

Cholesterol Clumps Disrupt the Pain Relief We Feel From Applying Pressure

Physical pressure on an injury can reduce pain signals, but new research shows that cholesterol clumps in cell membranes can interfere with that process.
A microscope lens pointed at a slide.

Reimagining Electron Microscopy: Bringing High-End Resolution to Low-Cost Microscopes

Researchers have shown for the first time that expensive aberration-corrected microscopes are no longer required to achieve record-breaking microscopic resolution.
Stem cells.

Light Sheet Microscopy Offers New Insights on Stem Cell Fate

Researchers at Duke University have been making movies by peering at stem cells near the root’s tip and taking snapshots as they divide and multiply over time, using a technique called light sheet microscopy.
Bacteria growing on an agar plate.

Key to Targeting Antibiotic-Resistant Bacteria Lies in Their Biofilm Arrangement

Researchers had assumed that bacteria were arranged somewhat randomly in biofilms. New research shows that bacteria that form biofilms actually have a highly structured arrangement within those slimy matrices.
Three in-focus cells with many more out of focus behind them.

Cells Respond Quickly to Small Light-Induced Micro-Environment Movements

Cells can quickly detect and respond to minor changes in their environment, and their response is more complex than expected, reports new research.
A model of a human heart.

Discovery of Key Protein Interactions as Potential Heart Disease Biomarker

Investigators have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function. The findings highlight a novel mechanism for MyBP-HL in regulating atrial relaxation and function.