Neurodegeneration – News and Features

A 30-year study of 47,000 women found that consuming high-quality carbohydrates and fiber during midlife improves odds of healthy aging. Diets rich in whole grains, fruits and vegetables supported better physical and cognitive health.

A UT Health San Antonio-led study shows elevated cortisol in midlife correlates with increased amyloid protein deposits in post-menopausal women’s brains. Researchers highlight stress hormone’s role in early Alzheimer’s risk.

Researchers from the Keck School of Medicine of USC have developed a blood test that can identify early signs of Alzheimer’s disease by measuring proteins linked to the condition.

UVA Health researchers developed a non-invasive focused ultrasound method with microbubbles that stops the growth of cerebral cavernous malformations (CCMs) in mice. The approach temporarily opens the blood-brain barrier without drugs.

UCL researchers have discovered a second dopamine-based learning system in the brain that reinforces repeated actions without regard to outcome. This “action prediction error” signal helps form habits and may explain why certain behaviors persist.

Discover how scientists imaged the Parkinson’s protein PINK1, unlocking insight into its role in mitochondrial quality control and brain cell survival.

Northwestern scientists developed a nanofiber therapy that halts toxic protein clumping in diseases like Alzheimer’s and ALS. These sugar-coated fibers trap misfolded proteins before they can damage neurons.

A new study suggests estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue in metabolic disorders like cancer and multiple sclerosis.

A clinical trial has found that low-dose interleukin-2 is both safe and effective for use on people with motor neuron disease, also known as amyotrophic lateral sclerosis (ALS), compared to a placebo.

A new study from Vanderbilt and Pitt links prolonged sedentary behavior to cognitive decline and brain shrinkage in aging adults. The association held even among those who exercised, and was stronger in people with the APOE-e4 gene.