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Neurodegeneration – News and Features

A model of a spine, with vertebrae shown in white and the spinal cord in red and yellow.
News

"Cellular Bridges" Help Repair Spinal Cord After Injury

Tiny cells inside small blood vessels called pericytes can be forced to change shape and create "cellular bridges" that support axon regeneration after spinal cord injury.
Young girl wearing noise-canceling headphones and a yellow hoodie, often used for autism sensory support.
News

Autism and Myotonic Dystrophy Share Genetic Link

A study identifies a genetic link between autism and myotonic dystrophy type 1 (DM1). Researchers found that tandem repeat expansions in the DMPK gene, causing DM1, also disrupt gene splicing in the brain.
Illustration of neurons with amyloid plaques, representing cognitive decline and neurodegeneration.
News

Exercise May Slow Brain Aging and Cognitive Decline

A UT Southwestern study finds that higher cardiorespiratory fitness may slow age-related brain atrophy, preserving cognitive function. The study showed that those with better physical fitness had larger brain volumes and better cognitive performance.
Doctor pointing at brain scan images on a screen, analyzing for signs of Alzheimer's disease.
News

Age, Sex and Genetics Affect Blood Biomarkers for Dementia

A long-term study reveals how age, sex, genetics, and menopause influence blood biomarkers related to dementia. The study tracked neurofilament light chain proteins, glial fibrillary acidic proteins, and phosphorylated tau 181.
Diagram and microscopy images showing a cannula system implanted in a mouse brain for in vivo imaging.
News

Cannula System Enhances Brain Imaging in Neuroscience

Researchers at Massachusetts General Hospital developed a novel cannula delivery system for effective compound administration during multiphoton microscopy, allowing for extended in vivo brain imaging.
Detailed digital rendering of interconnected neurons and blood vessels in the human brain.
News

Gene-Targeting Drugs That Can Overcome the Blood-Brain Barrier

Researchers at Tokyo University of Science have developed Chol-HDOs, which efficiently penetrate the brain, overcoming challenges associated with delivering gene-targeting drugs to brain tissue.
Close-up of a neuron, the key component of a new cell therapy for Parkinson's disease.
News

Dopamine-Producing Cell Therapy Shows Promise in Parkinson's Trial

Researchers have developed a treatment for Parkinson’s disease that involves creating nerve cells from embryonic stem cells and transplanting them into patients. Early results show the treatment is safe and may improve Parkinson’s symptoms.
A person holding a drug pen used to administer weight loss drugs, which have been linked to a lower risk of dementia.
News

Could Weight Loss Drugs Be Repurposed as Dementia Treatments?

Weight loss drugs, including GLP-1RAs, might offer new ways to reduce dementia risk. Discover the latest research and what it means for Alzheimer's treatment.
A doctor examines multiple brain scans on a screen using a pen to point at the images, possibly related to Alzheimer's disease.
News

Alzheimer’s Disease Could Be Detected 11 Years Early With New Blood Biomarker

A study identifies beta-synuclein in blood as a potential early biomarker for Alzheimer’s disease. This protein’s levels rise 11 years before cognitive symptoms, offering promise for early diagnosis and improved treatment outcomes.
Close-up of cannabis plant leaves and buds in an outdoor cultivation setting.
News

23% Increased Dementia Risk for Cannabis Users

A new study reveals that individuals aged 45 and older who had an emergency department visit or hospitalization due to cannabis were at 23% and 72% greater risk of developing dementia within five years compared to other groups.
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