Neurodegeneration – News and Features

A new technique has provided a lens through which to view the proteins responsible for synaptic transmission during memory and learning.

Failure of a gene-reading quality-control mechanism called Integrator leaves cells littered with abnormal RNA strands that increase cell stress and may contribute to diseases such as cancer and neurodegeneration.

Discover how epiproteomics unlocks new biomarkers and drives breakthroughs in diagnostics and drug development.

The study found elderly women were far less likely to have extensive build-up of abdominal aortic calcification if they consumed a high level of flavonoids in their diet.

Researchers have elucidated the mode of action of a promising inhibitor of a Parkinson's-associated mitochondrial protein.

A new study finds that RNA editing by ADAR1 in astrocytes contributes to neuroinflammation in Parkinson’s disease. Using patient-derived iPSC models, researchers show how ADAR1 promotes inflammation by focusing on genes involved in immune responses.

Reduced levels of the TDP-43 protein have been linked to brain diseases like Alzheimer’s, frontotemporal dementia and ALS, through its link to the brain's blood vessels.

A study reveals that retinal responses to light in Parkinson’s patients differ from healthy individuals. This could pave the way for a simple, non-invasive method for early Parkinson’s diagnosis, allowing for earlier interventions.

A new atlas of the mouse brain has been developed that will increase precision in measuring changes in brain structure and make it easier to share results for scientists working to understand neurological diseases such as Alzheimer's disease.

A study reveals that immune system proteins play a role in mental health conditions such as depression, schizophrenia and Alzheimer’s. Researchers identified 29 immune-related proteins that could contribute to these conditions.