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Neurodegeneration – News and Features

A synapse with neurotransmitters and receptors, a process during memory formation.
News

Mapping the Molecular Underpinnings of Memory Formation

A new technique has provided a lens through which to view the proteins responsible for synaptic transmission during memory and learning.
A double-stranded helix of DNA forms a loop and breaks, symbolising DNA damage and quality control failure.
News

How Cellular Quality Control Failure Leads to Cancer and Neurodegeneration

Failure of a gene-reading quality-control mechanism called Integrator leaves cells littered with abnormal RNA strands that increase cell stress and may contribute to diseases such as cancer and neurodegeneration.
Lab technician examining a blood sample in a modern laboratory for diagnostic blood testing.
Article

Epiproteomics Could Advance Biomarker Discovery and Patient Care

Discover how epiproteomics unlocks new biomarkers and drives breakthroughs in diagnostics and drug development.
A bowl of tea next to a wooden spoon of dried tea leaves and other organic items.
News

Black Tea May Contribute to a Healthier Later Life

The study found elderly women were far less likely to have extensive build-up of abdominal aortic calcification if they consumed a high level of flavonoids in their diet.
White pills in front of an MRI scan of the brain, indicating understanding of drug mechanism.
News

Uncovering How a Promising Parkinson's Drug Works

Researchers have elucidated the mode of action of a promising inhibitor of a Parkinson's-associated mitochondrial protein.
A close-up of a hand holding tweezers to modify the structure of DNA, illustrating RNA editing or gene editing technologies.
News

RNA Editing's Role in Neuroinflammation in Parkinson's Disease

A new study finds that RNA editing by ADAR1 in astrocytes contributes to neuroinflammation in Parkinson’s disease. Using patient-derived iPSC models, researchers show how ADAR1 promotes inflammation by focusing on genes involved in immune responses.
Gold-colored neural cells forming connections.
News

Protein Links Leaky Blood Vessels to Brain Diseases

Reduced levels of the TDP-43 protein have been linked to brain diseases like Alzheimer’s, frontotemporal dementia and ALS, through its link to the brain's blood vessels.
Close-up of a human eye showing intricate details of the iris and pupil.
News

Early Parkinson’s Diagnosis Could Be Possible Using Retinal Light Responses

A study reveals that retinal responses to light in Parkinson’s patients differ from healthy individuals. This could pave the way for a simple, non-invasive method for early Parkinson’s diagnosis, allowing for earlier interventions.
A map of a mouse brain, with sections labelled in blue, green, pink and red.
News

New Mouse Brain Atlas Enhances Neurodegenerative Disease Research

A new atlas of the mouse brain has been developed that will increase precision in measuring changes in brain structure and make it easier to share results for scientists working to understand neurological diseases such as Alzheimer's disease.
Silhouetted person sitting alone in a dark hallway, conveying feelings of depression and isolation.
News

Immune System’s Role in Depression and Schizophrenia Revealed

A study reveals that immune system proteins play a role in mental health conditions such as depression, schizophrenia and Alzheimer’s. Researchers identified 29 immune-related proteins that could contribute to these conditions.
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