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Neurodegeneration – News and Features

Drug capsules placed on a target, illustrating drug targets and target-based drug discovery.
News

Mitochondrial Protein Discovery Offers Avenue for Alzheimer's Therapeutics

The mitochondrial protein that controls calcium transport could be a promising target for Alzheimer's and heart disease drugs.
3D illustration of mitochondria showing internal membrane structure and proteins involved in energy production.
News

Mitochondrial Proteins Act as Guardians in Parkinson’s Disease

Researchers at Johns Hopkins Medicine discovered that mitochondrial proteins Parkin, PINK1, and OMA1 act as guardians of mitochondrial size and function, playing crucial roles in the development of Parkinson’s disease.
Neural cells, with protrusions reaching across the image, illustrating neural regeneration.
News

Newly Generated Neurons May Repair Damage in Huntington's Disease

The adult brain can generate new neurons that integrate into key motor circuits, helping to repair damaged neural networks in Huntington's disease.
Scientists in a laboratory analyzing blood samples for biomarker research, wearing gloves and masks.
Article

Advances in Biomarker Discovery and Analysis

Explore how proteomics, AI and microsampling are advancing biomarker discovery. Learn how these innovations are shaping the future of precision medicine.
Visualization of the small and large intestines showing a range of bacteria, representing the gut microbiome.
News

Could Your Gut Microbiome Make Certain Drugs Less Effective?

New findings on how the gut microbiome influences drug metabolism and effectiveness could open the door to personalized medicines and better treatment outcomes.
3D rendering of human cells with visible nuclei, illustrating concepts in cell science.
News

New Tool Pinpoints Cells That Promote Disease

A new computational tool can pinpoint cells that promote health or disease, categorizing thousands of cells into biologically distinct groups.
Healthcare worker administering a shingles vaccine to an older adult wearing a face mask.
News

Shingles Vaccine Reduces Dementia Risk by 20%

A study found that individuals who received the vaccine were 20% less likely to develop dementia over seven years. The researchers demonstrated a potential causal link between shingles immunization and reduced dementia risk.
A mitochondrion, bisected to reveal the internal membranes.
News

Specialized Recycling System Eliminates Faulty Mitochondrial DNA

New research illustrates how cells with defective mitochondria activate a special recycling system to eliminate damaged genetic material.
A hand holding a detailed model of a kidney, showing internal structures including blood vessels and the renal system.
News

New Method Enhances Understanding of Polycystic Kidney Disease

A study from Rutgers University presents a new method for tracking polycystin proteins in polycystic kidney disease (PKD). Using C. elegans as a model, researchers employed fluorescent proteins to observe protein movement and interactions.
A detailed model of a human heart, representing cardiovascular health in the context of Parkinson's disease research.
News

Parkinson’s Disease Impacts the Heart, Not Just the Brain

Researchers at the University of Surrey discovered that Parkinson’s-related alpha-synuclein accumulates in the heart’s nerve clusters, suggesting that Parkinson’s affects heart function, not just brain and movement.
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