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Neurodegeneration – News and Features

A holograph of a lung-on-a-chip, one of the human-based technologies the NIH is prioritizing to reduce animal testing.
News

NIH Announces Plans To Prioritize Human-Based Technologies in Research

The National Institutes of Health (NIH) is adopting a new initiative to expand the use of innovative, human-based technologies such as organoids and organ-on-a-chip, while reducing animal use in research.
Orange and white drug capsules spill from a prescription bottle.
News

How Antipsychotics Cause Parkinson's Disease-Like Side Effects

Researchers have uncovered the molecular mechanisms that cause a commonly prescribed antipsychotic drug to produce harmful side effects similar to Parkinson’s disease symptoms.
A woman jogging in a park, smiling and wearing an orange hoodie and fitness gear, promoting the benefits of regular exercise.
News

Exercise Reduces Alzheimer’s Disease Risk

A study found that increasing physical activity in middle-aged adults can reduce Alzheimer's risk by lowering beta-amyloid accumulation in the brain. The research highlighted the benefits of even minimal exercise.
A person in bed, holding their forehead in distress, surrounded by soft lighting and a bedside clock, indicating the challenges of sleep disorders.
News

Sleep Deprivation and Sleep Disorders Affect Brain Regions Differently

A new meta-study examines the brain regions affected by chronic sleep disorders and short-term sleep deprivation. Researchers found that chronic sleep disorders alter regions like the anterior cingulate cortex and hippocampus.
Laser spotlights above a stage
News

Light-Based Data Made Clearer With New Machine Learning Method

A new machine learning algorithm excels at interpreting optical spectroscopy data of molecules, materials and disease biomarkers, potentially enabling faster and more precise medical diagnoses and sample analysis.
An outline of a brain in fluorescent green against a black background, representing the brain on psilocybin.
News

Psilocybin Improves Mood and Motor Function in Parkinson's Patients

In a pilot study testing psilocybin therapy in Parkinson's patients, the participants experienced clinically significant improvements in mood, cognition and motor function that lasted for weeks after the drug was out of their systems.
Close-up of neurons with highlighted synaptic connections, illustrating the complex changes seen in Alzheimer's disease.
News

Synthetic Tau Protein Fragment Mimics Prion Behavior

Researchers have created the first synthetic fragment of tau protein that behaves like a prion. This synthetic fragment forms prion-like fibrils that propagate misfolding, advancing understanding of tau-related neurodegenerative diseases.
A neuron forms dendrites, reaching out across a grey background.
News

Why Some Nerve Cells Are Resistant to Dementia

A research team has found molecular clues as to why some nerve cells die in dementia and not others, in a new study in fruit flies.
Digital rendering of a brain with a glowing neural network pattern on a blue background.
News

Brain Mechanism Reveals How We Quickly Switch Motor Actions

esearchers at USC have discovered a new brain mechanism that allows humans to rapidly switch between motor actions. This process does not involve stopping the initial movement, as previously believed.
Three middle-aged women smiling and talking outdoors on a sunny day, representing menopause support.
News

Iron Deficiency May Contribute to Cognitive Decline in Menopausal Women

New research shows that women transitioning into menopause who maintain adequate iron levels perform better on cognitive tasks. The study found no link between blood iron and brain iron accumulation.
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