Neurodegeneration – News and Features

News
Newly Identified Neural Stem Cells Could Transform Parkinson's Treatment
The detection of peripheral neural stem cells could transform the treatment of Parkinson's disease and spinal cord injuries.

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First Down Syndrome Participant Dosed in Trial of Alzheimer’s Treatment
Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor protein for the potential treatment of Alzheimer’s disease.

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Protein Involved in Parkinson’s Disease Also Drives Skin Cancer
A study suggests new avenues for drug development to reduce the risk of developing both Parkinson’s and skin cancer by targeting the function of the alpha-synuclein protein, which appears to have a critical role in regulating cellular functions.

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Eight Alcoholic Drinks a Week Raises Brain Lesion Risk
Researchers examined brain tissue to look for signs of brain injury including tau tangles and hyaline arteriolosclerosis.

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Vitamin K Deficiency Linked to Memory and Brain Cell Decline
A recent study at Tufts University showed that vitamin K deficiency in mice led to impaired memory, reduced neurogenesis, and increased brain inflammation. These findings suggest that vitamin K plays a crucial role in supporting brain health.

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Low Levels of "Bad" Cholesterol Linked to Reduced Dementia Risk
People with low levels of low-density lipoprotein cholesterol (LDL-C) in their blood have a lower risk of dementia, a new study reports.

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Natural Antioxidant Slows Nerve Cell Damage in Cells From ALS Patients
In lab-grown nerve cells from ALS patients, a natural compound found in certain fruits and vegetables helped the cells produce more energy and eased stress in the protein-processing center of the cell called the endoplasmic reticulum.

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Tolebrutinib Demonstrates a Delay in Disability Progression in MS Clinical Trial
A clinical trial of tolebrutinib, an investigational oral Bruton’s tyrosine kinase inhibitor, demonstrated a 31% delay in the onset of six-month confirmed disability progression in patients with non-relapsing secondary progressive multiple sclerosis.

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Water Filter With Nanoscale Channels Removes Stubborn PFAS
Researchers have developed a new filter membrane that can efficiently remove short-chain PFAS from water. Previous treatments could only remove around 25% of these molecules from water.

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Nanoparticles Deliver Anti-Inflammatory Medicine to the Brain
Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of neurodegenerative diseases.
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