Neurodegeneration – News and Features

The detection of peripheral neural stem cells could transform the treatment of Parkinson's disease and spinal cord injuries.

Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor protein for the potential treatment of Alzheimer’s disease.

A study suggests new avenues for drug development to reduce the risk of developing both Parkinson’s and skin cancer by targeting the function of the alpha-synuclein protein, which appears to have a critical role in regulating cellular functions.

Researchers examined brain tissue to look for signs of brain injury including tau tangles and hyaline arteriolosclerosis.

A recent study at Tufts University showed that vitamin K deficiency in mice led to impaired memory, reduced neurogenesis, and increased brain inflammation. These findings suggest that vitamin K plays a crucial role in supporting brain health.

People with low levels of low-density lipoprotein cholesterol (LDL-C) in their blood have a lower risk of dementia, a new study reports.

In lab-grown nerve cells from ALS patients, a natural compound found in certain fruits and vegetables helped the cells produce more energy and eased stress in the protein-processing center of the cell called the endoplasmic reticulum.

A clinical trial of tolebrutinib, an investigational oral Bruton’s tyrosine kinase inhibitor, demonstrated a 31% delay in the onset of six-month confirmed disability progression in patients with non-relapsing secondary progressive multiple sclerosis.

Researchers have developed a new filter membrane that can efficiently remove short-chain PFAS from water. Previous treatments could only remove around 25% of these molecules from water.

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of neurodegenerative diseases.