Neurodegeneration – News and Features

This article explores some of the reasons animal models are used in neuroscience and how this could change in the future.

Metabolomics is expected to increasingly impact precision medicine and diagnostics.

A study using ASPREE trial data shows men carrying two copies of the HFE H63D variant have over double the lifetime risk of dementia. This increased risk was not seen in women, and blood iron levels did not explain the risk.

Researchers at Mass General Brigham have developed a diagnostic tool called Luminescence CAscade-based Sensor (LUCAS) that produces highly sensitive, rapid detection of viruses in complex biological samples.

New research offers clues into how APOE isoforms affect microglia function differently in Alzheimer's disease, leading to strikingly different risk profiles.

A study finds depression at any adult age increases the risk of dementia. Depression in late life may also signal early dementia onset. The findings underscore the need for early diagnosis and treatment of depression to help protect brain health.

Researchers found that immune T cells reside in healthy brains, signaling between the gut and brain, a previously unknown communication pathway. These cells, concentrated in the subfornical organ, are involved in regulating hunger and thirst.

Learn how CD34+ stem cells may help heart attack patients recover. A look at cutting-edge cell therapies and what's coming next in cardiac care.

Researchers show how directed motions combined with protein interactions influence phase separation and the maintenance of biomolecular condensates

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human aging, disease and even space travel, according to a new study.