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Single-Cell Analysis – News and Features

Dr. Sarah Teichmann standing next to a building and pond.
Article

From School Science Club to Cell Atlasing With Dr. Sarah Teichmann

In this interview, Dr. Sarah Teichmann shares insights into her research interests, the goals and progress of the HCA to date, as well as her thoughts on how women can begin and build successful careers in science.
Cancer cells.
News

Biomarkers Linked to Cell Therapy Response for Bone Marrow Tumors Identified

In a recent clinical study, researchers identified several biomarkers that are associated with the response to CAR T cell therapy in multiple myeloma, a malignant tumour disease in the bone marrow.
A 3D model of human lungs.
News

Harmless Particles Found To Improve Immune Response

The immune system trains its response whenever it encounters such a pathogen. Yet researchers at the University of Bonn have now shown that even harmless particles help to improve the immune response.
Cancer cells.
News

Pre-Ketone Supplement With Immunotherapy Shows Promise for Prostate Cancer in Mice

Adding a pre-ketone supplement – a component of a high-fat, low-carb ketogenic diet – to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer.
Illustration of a human form
Article

Dissecting the Proteome To Understand Disease

Proteomics provides insights into the regulation of biological processes and mechanisms of disease. In this article, we explore approaches scientists are using to find early markers of disease, new drug targets and strategies to overcome resistance to treatments.
Multimodal analyses of cells from abnormal tunnels in Crohn's disease converge to illuminate underlying pathomechanisms.
News

Single-Cell Analysis Reveals Mechanism of Common Crohn’s Disease Complication

Study identifies key pathways underlying perianal fistula, a complication that is more prevalent and severe in African American populations.
Cancer cells.
News

Study Uncovers Potential Immunotherapy Approach for Rare Eye Cancer

New research explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy can successfully treat this rare and aggressive cancer.
Red blood cells in a blood vessel.
News

Novel Cell Type in Blood Vessels Found Responsible for Vascular Growth

The discovery of a new cell type responsible for vascular growth could allow for novel treatment strategies for some cardiovascular disease.
COVID-19.
News

Nasal Cells Specific to Children Protect Against COVID-19

Important differences in how the nasal cells of young and elderly people respond to the SARS-CoV-2 virus, could explain why children typically experience milder COVID-19 symptoms, finds a new study.
A cell with small internal compartments visible.
News

Chromosome Locations in Individual Cells Revealed by Machine Learning

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell.
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