Fit-for-Purpose Biomarker Assay Validation - From Research Tool to Diagnostic Test
Jeff Cummings presents a worked example of circulating tumour cell enumeration as a prognostic/predictive biomarker in cancer research.
Biomarkers to Predict Aggressive Prostate Cancer
Claire Morgan discusses the need to identify a panel of biomarkers that may distinguish indolent cancer from aggressive metastatic disease when used collectively.
Tumour Regression after Intravenous Administration of Novel Tumour-targeted Nanomedicines
In this talk, Christine Dufes demonstrates that the intravenous administration of a tumour-targeted dendriplex led to tumour disappearance of 90% of the tested tumours over one month.
Magneto-plasmonic Nanoparticle Platform for Capture, Separation and Enumeration of Rare Cells
In this presentation we will explore the opportunities afforded by the hybrid magneto-plasmonic nanoparticles and PA imaging for the development of a low cost simple and nearly real-time assays for capture, separation and enumeration of rare cells.
Green Nanotechnology in Cancer Therapy
In this talk Kattesh Katti, describes the application of green nanotechnology in cancer therapy.
Microfluidic Systems for Biomarker Analysis and Cancer Diagnosis
In this talk, Martin Gijs discusses a novel magnetic surface coverage assay and a microfluidic tissue processor with applications in cancer diagnostics.
Detection and Expression Profiling of Tumor Initiating Cells (TIC) Among the Peripherally Circulating Epithelial Tumor Cells from Patients with Breast Cancer
Katharina Pachmann shows that among the peripherally circulating tumor cells a variable fraction is able to express stem cell and adhesion properties and can be grown into tumor spheres, a property ascribed to cells capable of initiating tumors and metastases.
Monitoring Dynamic Interactions of Tumor Cells with Tissue and Immune Cells in a Lab-on-a-Chip
Peter Ertl discusses how for the first time, direct cell-to-cell interactions of tumor cells with bead-activated primary T cells were continuously assessed using an effector cell to target cell ratio of 10:1.
Improvements in Molecular Diagnosis of Pathogens and Diseases
This talk offers a valuable guide to the development of LAMP in molecular detection and determination of target sequences and will present examples with bright field applications of the method from the detection of pathogens to clinical applications for the diagnosis of cancer and other disorders.
DNA Methylation and the Cancer Epigenome Biological and Translations Implications
In this talk, Stephen Baylin, discusses the development of strategies for “epigenetic therapies” for cancer and biomarker development.