Cancer Cells Communicate – But What If We Could Interrupt Them?

As part of the London Proteomics Discussion Group webinar series: "SARS-CoV-2: What role can proteomics play?" Dr Münch presented his work on changes in response to SARS-CoV-2 infection, highlighting potential therapies.

When a cell divides to make new cells, the chromosomes normally stay the same. But sometimes mistakes happen. With Philadelphia positive leukemia, a gene called the ABL1 gene on chromosome 9 breaks off and sticks to a gene called the BCR gene on chromosome 22. It produces a new gene called BCR-ABL1 which causes the cell to make too much of a protein called tyrosine kinase. This protein encourages leukemia cells to grow and multiply.

This 3D medical animation explains what a pandemic is, rates of infection and ways to protect against infections. It also delves into the biology and mechanism of action (MoA) that coronavirus uses to infect and destroy human cells. Though the exact MoA for this coronavirus is not known.