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Applications of  Targeted Mass Spectrometry Assays for Quantitative Analysis of Cancer Signaling Proteins


Proteomics offers a deeper understanding of the protein events influencing various cellular and biological functions. However, identifying key regulated proteins and their implicated signaling pathways represents a major analytical challenge to researchers. This is due to the broad dynamic range of protein abundance in biological samples and the inherent limitations of the instrumentation and methodologies utilized to probe and detect minute target proteins in complex cellular environments.

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