In this webinar, our expert speaker Dr. Simon Reed from Broken Strings Bioscience will discuss the background to this industry-wide challenge and the need for technological advancements in this space.

MALDI mass spectrometry imaging has emerged as a powerful technology platform for spatially resolved analysis and visualization of a wide range of molecules – including drugs, metabolites, peptides and more – in pharmaceutical R&D, clinical research and basic science. Advances in MALDI workflows are making the technique more accessible.
In this webinar, our speaker will discuss how a new MALDI workflow can be used to analyze lipids in degenerative disease and Alzheimer’s models, contextualizing lipid distribution by enabling comparison to multiple protein markers.
He’ll also highlight how the new workflow can be applied to the study of tumor subtypes and the tumor microenvironment.

Immune cell activation, differentiation and function are metabolically demanding processes, and it has now become clear that nutrient access and metabolism play a major role in regulating lymphocyte fate and function. These axes of regulation are crucially important in shaping the immune system when it is activating in metabolically demanding environments, such as tumor tissue. Indeed, the immune response to cancer is characterized by several metabolic defects. In this webinar, Dr. Delgoffe will discuss some of these metabolic insufficiencies within the T cell compartment of solid tumors and reveal novel insights into how these metabolic nodes may be modulated to improve the immune response to cancer.

Key advances will be highlighted across the field of immuno-oncology. Hear a cross-section of experts discuss their research with a focus on basic research and a broad range of established and novel immunotherapeutics.

The liver is the most common metastatic site for many primary tumors. Single-cell gene and protein expression, in combination with spatial data that contextualizes relationships with other tumor cells and structures, are critical to fully understand how cells communicate in liver metastases.
Resolving the precise spatial location of each single cell allows for a comprehensive understanding of the tissue architecture for each tumor and helps identify critical cell–cell communication circuits.
This webinar will highlight approaches to generating a spatial atlas of tumors, illustrate how to integrate single-cell transcriptomics data with spatial data and explore how to track cell behavior to study cell–cell interactions in each cellular neighborhood.

In this webinar, we’ll explore how integrating proteomics with systems biology sheds light on the complexities of AD pathology.