Engineering Adoptive T-Cell Therapy To Overcome Immune Suppression in Ovarian Cancer
In this webinar, Dr. Kristin G. Anderson, Research Associate from the Greenberg lab at the Fred Hutchinson Cancer Research Center, discusses engineering T cells to improve survival in the immunosuppressive tumor microenvironment.
Watch the webinar on demand to learn about:
- Hurdles that T cells must overcome to beat ovarian cancer, including anti-tumor T cell death which results in tumor escape
- Engineering T cells with a protein that converts a death signal into a survival signal to prolong survival of tumor-bearing mice compared to T cells with only a TCR
- How xCELLigence RTCA instruments can be used to directly measure T cell killing in vitro in a simple and high throughput workflow
Dr Kristin Anderson