Integrating Nanopore Sequencing Into Clinical Research: Case Studies in Pathogen, Cancer and Genomics Analysis

Integrating Nanopore Sequencing Into Clinical Research: Case Studies in Pathogen, Cancer and Genomics Analysis Long-read sequencing provides advantages over short reads for a multitude of applications including characterizing pathogens, analyzing cancer genomic alterations and accurately detecting structural variants in the human genome. In this webinar, Dr. Alfredo Hildalgo will demonstrate the potential and flexibility of Oxford Nanopore Technologies’ sequencing platforms in cancer and infectious disease research. He will showcase the use of the Oxford Nanopore sequencing platform to sequence SARS-CoV-2 and Mycobacterium tuberculosis to monitor viral evolution and drug resistance. Dr. Hildalgo will also highlight the transcriptomic analysis, characterization of chromosomal translocations and the identification of mutations with diagnostic potential in lymphoblastic leukemia samples. • Understand how long-read sequencing can be applied to characterize pathogens and monitor viral evolution and drug resistance • Learn how nanopore sequencing supports transcriptomic analysis in cancer research, including subtype identification in acute lymphoblastic leukemia • Explore how PromethION sequencing enables detection of structural genomic alterations, such as chromosomal translocations and disease-associated mutations • Gain insights into practical considerations for long-read sequencing workflows, including for yield, read length and flow cell reuse Alfredo Hidalgo Miranda Principal Investigator Instituto Nacional de Medicina Genomica, Mexico Esmeralda Garcia Account Manager Oxford Nanopore Technologies