Latest Whitepapers

Studying the tumor microenvironment (TME) helps improve our understanding of cancer. Myeloid-derived suppressor cells (MDSCs) exist within the TME and maintain cancer progression.

Determining cell viability is a vital component in many biological experiments and one of the most common methods for this measurement is the trypan blue (TB) exclusion assay.

Chimeric antigen receptor (CAR) T-cell therapy is a revolutionary and promising approach for cancer treatment. However, its potential is limited by technical challenges and safety risks associated with viral transduction–based CAR T-cell generation workflows.

While next-generation sequencing is becoming increasingly routine in cancer research laboratories, it fails to address a number of key genomic drivers or markers of cancer, such as structural variations, DNA methylation and transcript isoforms.

Cancer immunotherapy, especially the use of immune checkpoint inhibitors, has been successful in improving the treatment landscape of malignancies.

Download this whitepaper to discover how high-throughput flow cytometry can provide quantitative data on binding, antibody internalization and antibody-dependent cell-mediated cytotoxicity, antibody-dependent cellular phagocytosis and T-cell activation.

Primary antibody labeling simplifies assays, enables multiplexing and eliminates the cross-reactivity seen with secondary antibodies – helping you to streamline your workflow, increase your flexibility and improve reproducibility.

Creating and bringing new drugs to the market can bring huge productivity challenges as the already complex drug development process becomes lengthier and more expensive.

Immunotherapy has the potential to treat a wide variety of conditions, from autoimmune disease to cancer. However, the discovery of potential antibody therapeutics against key receptor proteins remains a major challenge for the traditional immunisation approaches currently available on the market.

Currently, various treatments are available to cancer patients, such as chemotherapy, targeted therapy and immunotherapy. Targeted therapy is a type of precision medicine that targets the proteins that control the growth, division and spread of cancer cells.