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Latest Whitepapers

Whitepaper

Therapies Targeting Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

Studying the tumor microenvironment (TME) helps improve our understanding of cancer. Myeloid-derived suppressor cells (MDSCs) exist within the TME and maintain cancer progression.
Whitepaper

Comparison of Viability Detection Methods Via Morphological Observation

Determining cell viability is a vital component in many biological experiments and one of the most common methods for this measurement is the trypan blue (TB) exclusion assay.
Whitepaper

An Optimized Workflow for Generating Anti-CD19 CAR T Cells by mRNA Electroporation

Chimeric antigen receptor (CAR) T-cell therapy is a revolutionary and promising approach for cancer treatment. However, its potential is limited by technical challenges and safety risks associated with viral transduction–based CAR T-cell generation workflows.
Whitepaper

Accelerating Cancer Research Through Comprehensive Genomic Analysis

While next-generation sequencing is becoming increasingly routine in cancer research laboratories, it fails to address a number of key genomic drivers or markers of cancer, such as structural variations, DNA methylation and transcript isoforms.
Whitepaper

PD-1/PD-L1 Combination Therapy in Cancer Treatment

Cancer immunotherapy, especially the use of immune checkpoint inhibitors, has been successful in improving the treatment landscape of malignancies.
Whitepaper

High-Throughput, Multi-Parametric Analysis Accelerates Antibody Discovery Workflows

Download this whitepaper to discover how high-throughput flow cytometry can provide quantitative data on binding, antibody internalization and antibody-dependent cell-mediated cytotoxicity, antibody-dependent cellular phagocytosis and T-cell activation.
Whitepaper

Streamline Antibody Labeling Workflows

Primary antibody labeling simplifies assays, enables multiplexing and eliminates the cross-reactivity seen with secondary antibodies – helping you to streamline your workflow, increase your flexibility and improve reproducibility.
Whitepaper

Improving Efficiency in Drug Discovery and Preclinical Development

Creating and bringing new drugs to the market can bring huge productivity challenges as the already complex drug development process becomes lengthier and more expensive.
Whitepaper

Antibody Candidates Against GPCR Therapeutic Targets

Immunotherapy has the potential to treat a wide variety of conditions, from autoimmune disease to cancer. However, the discovery of potential antibody therapeutics against key receptor proteins remains a major challenge for the traditional immunisation approaches currently available on the market.
Whitepaper

Research Tools for Anti-Cancer Drug Targets

Currently, various treatments are available to cancer patients, such as chemotherapy, targeted therapy and immunotherapy. Targeted therapy is a type of precision medicine that targets the proteins that control the growth, division and spread of cancer cells.
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