Latest Whitepapers
Whitepaper
Antibody–Drug Conjugates: A Novel Paradigm for Cancer Therapy
This whitepaper highlights the key molecular components of ADCs and the challenges and opportunities for their future development.
Whitepaper
Enhanced CD8+ T Cell Isolation From Mouse Tumors: SimpleFlow vs Enzymatic Methods
Tissue dissociation is a crucial sample preparation step that enables the isolation of specific cell populations for downstream applications such as single-cell RNA sequencing. Enzymatic tissue dissociation is widely used, but some researchers have concerns about the impact of enzymes on cell marker expression.
Whitepaper
Tumor Exosomes: A Messenger for Cancer Progression
This whitepaper explores the role of extracellular vesicles in cell-to-cell communication during cancer progression. It also highlights a range of high-quality recombinant proteins, antibodies and cytokines and to support exosome research.
Whitepaper
A Guide to Cell Culture Success
Cell culture is essential for a variety of applications including disease modeling, drug discovery, cell-based manufacturing and genetic engineering.
Whitepaper
How To Accelerate and De-Risk Drug Development in Oncology
Although there are initiatives to de-risk the drug development process, continually applying the same tools and approaches is unlikely to lead to innovative, first- or best-in-class targets and transformative progress.
Whitepaper
The End of End-Point Assays
This whitepaper highlights the recent developments and performance of three modular benchtop solutions for the high-performance quantitation and kinetics characterization of proteins and their small molecule interactions.
Whitepaper
Streamlining Affinity Analysis for Accelerated Drug Discovery
This whitepaper highlights the features and capabilities of a novel system for streamlining affinity analysis for rapid lead molecule screening.
Whitepaper
How Spatial Phenotyping Can Uncover Novel Insights in Tissue Biology
Rather than choosing between the detail of single-cell RNA sequencing and the in situ capabilities of conventional immunohistochemistry, spatial phenotyping allow you to visualize and quantify dozens of biomarkers in a single tissue sample while maintaining cellular and sub-cellular detail.
Whitepaper
Investigating Cell-Free DNA in Liquid Biopsy
Only a small amount of cell-free DNA (cfDNA) can be found in circulation, therefore efficient and highly sensitive technologies such as next-generation sequencing (NGS) are typically being used to detect this biomarker.
Whitepaper
Therapies Targeting Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Studying the tumor microenvironment (TME) helps improve our understanding of cancer. Myeloid-derived suppressor cells (MDSCs) exist within the TME and maintain cancer progression.
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