Latest Whitepapers

Applying standard microscopy techniques on 3D cell cultures can be challenging. This white paper demonstrates how RAFT™ 3D Cell Cultures can be visualized with subcellular resolution under a standard fluorescence microscope.

Epigenetic regulation of genomic DNA for gene expression is important in cellular differentiation and the development of an organism. Epigenetics also contributes to human diseases. On a molecular level, epigenetics involves modification of the histone proteins and DNA that make up chromatin.

Here we show the development and implementation of a cost effective, no-wash HCA assay to simultaneously report the cell number, percentage of live cells and cell cycle phase distribution as markers of proliferation and viability.

: Many enterprises find themselves in need of a Laboratory Information Management System (LIMS) to replace an incumbent system, whether an existing commercial application, an amalgam of systems, or an in-house solution. Once the decision has been made, the selection and deployment of a new LIMS should move quickly and decisively. This white paper serves as a guide to selecting a commercial (LIMS).

Through the use of antibody-mediated fluorophore labelling of specific sub-populations of exosomes, phenotyping within complex mixtures can therefore be achieved.