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Developing Stem Cell Therapy Solutions for Liver Disease

Blog

We spoke with Eric Schuur, President and CEO of HepaTx, to learn how the company hopes to develop regenerative medicine solutions for people with liver disease. Eric provides an overview of the steps involved in hepatocyte production and provides insights on the hurdles that need to be overcome, to get these stem cells from the lab to the clinic.

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Streamline your western blotting workflow with iWestern

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Designed to address processing efficiency, reproducibility, and robustness of results, the iWestern Workflow helps to enable exceptional western blot results with minimal hands-on time.

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Through the Looking Glass of Single Cell Proteomics

Article

To pick apart the differences between individual cells in complex multicellular organisms, we need to look at cells one-by-one. This article takes a look at how several scientists in North America are using single cell proteomics (SCP) technologies to discern disease pathogenesis and enhance directed stem-cell differentiation.

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Answer the challenges of CDS Data integrity - Sterling Pharma Solutions Ltd

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Data integrity continues to be a hot topic for the regulatory agencies in the pharmaceutical industry.

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Identify and Quantify Individual Host Cell Proteins

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ELISA is the golden standard for HCP analysis but has some drawbacks. It only provides a single number (ng HCP/mg drug substance) and no information about the specific HCP’s.

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Stem Cell Transplant Variables That May Help Eradicate HIV
Stem Cell Transplant Variables That May Help Eradicate HIV
News

Study shows for the first time that stem cell source, time to achieve full replacement of recipient cells with donor cells, and graft-versus-host reactivity might contribute to HIV eradication.

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Transplanting More than Stem Cells to Restore Health
Transplanting More than Stem Cells to Restore Health
News

Using fecal transplants, researchers restored beneficial bacteria in cancer patients who received antibiotics for stem cell transplant procedures.

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Fish Oil may Help Fight Against Cancer
Fish Oil may Help Fight Against Cancer
News

Omega-3 fatty acids, such as those typically contained in fish oil, may suppress the growth and spread of breast cancer cells in mice.

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A Bad Influence: The Interplay Between Tumor & Immune Cells
A Bad Influence: The Interplay Between Tumor & Immune Cells
News

Research has yielded new insights into the environment surrounding different types of lung tumors, and described how these complex cell ecosystems may in turn ultimately affect response to treatment.

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Food or Sex?
Food or Sex?
News

Unicellular diatoms show complex behavior, selecting between the search for sex partners or nutrient sources based on an evaluation of their own needs.

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Neutrophil's Role During Tumor Progression Unraveled
Neutrophil's Role During Tumor Progression Unraveled
News

Neutrophils migrate from the bone marrow to distant sites and facilitate tumor cell seeding and establishment of metastasis.

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Understanding the Lytic Cycle – What Are the Steps?
Understanding the Lytic Cycle – What Are the Steps?
Article

Bacteriophage (phage) are viruses that specifically infect bacteria. They have a two-phase lifecycle, residing in a dormant state within the host genome (lysogenic cycle) or hijacking the host cellular machinery for their own replication (lytic cycle). Here we will explore the important steps of the lytic cycle.

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Chemical Snapshots and Molecular Maps with Mass Spec Imaging
Chemical Snapshots and Molecular Maps with Mass Spec Imaging
Article

Mass spectrometry imaging (MSI) is a powerful tool increasingly being used in many fields including cancer research, biomarker discovery and drug development. This article explains why MSI is the technique of choice in many labs, discusses its use in research, and covers how some inherent challenges are being addressed.

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Three Ways to Turn Life Science Suppliers into Partners
Three Ways to Turn Life Science Suppliers into Partners
Article

A growing number of life science businesses are turning to greater supply chain collaboration for benefits like accelerated time to market, improved quality, reduced risk and more rapid and widespread innovation. But while 68% of executives in this industry say active and meaningful engagement with suppliers is essential to success, far too many, over a third, struggle to implement it.

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Host Cell Protein Analysis in Biopharma
Host Cell Protein Analysis in Biopharma
Article

Presence of host cell protein (HCP) contaminants in the final product, even at very low levels, may elicit unpredictable and serious immunogenic response in humans. The accurate detection, identification and quantification of HCPs during biotherapeutic development is thus critical in ensuring patient safety, and is a regulatory requirement.

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Lytic vs Lysogenic – Understanding Bacteriophage Life Cycles
Lytic vs Lysogenic – Understanding Bacteriophage Life Cycles
Article

Bacteriophage (phage) are obligate intracellular viruses that specifically infect bacteria. Here we take an overview of their structure, life-cycle and the role they have played in advancing science and medicine.

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Imaging in Biology: How Many Words are Cell Images Worth?
Imaging in Biology: How Many Words are Cell Images Worth?
Article

They say 'a picture is worth a thousand words.' Is this true for cell images?

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