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CellStream™ Benchtop Flow Cytometer for Sensitive Cell Analysis

Video

The new CellStream™ benchtop flow cytometer delivers unparalleled sensitivity and flexibility for cell and particle analysis.

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Identify and Quantify Individual Host Cell Proteins

Webinar

ELISA is the golden standard for HCP analysis but has some drawbacks. It only provides a single number (ng HCP/mg drug substance) and no information about the specific HCP’s.

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Cell Culture Basics

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An overview of aseptic techniques

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Inhaled Bacteria Thwarted by Exosome-mediated Immune Surveillance

Inhaled Bacteria Thwarted by Exosome-mediated Immune Surveillance

News

What happens when cells at the front of your nose detect bacteria?

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Membrane Proteins Ejected Directly from Cell Membrane to Mass Spec
News

A new approach to analyzing cell membrane proteins in situ could revolutionize the way in which we study diseases, such as cancer, metabolic and heart diseases.

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Leukemia Stem Cells Rely on Amino Acids for Survival
News

Clinically relevant eradication of leukemia stem cells could be achieved with drugs that target their metabolic vulnerabilities.

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Ketone Shuttle Coordinates Response to Liver Fibrosis
News

A metabolite shuttle, or dialogue, provides a connection between hepatocyte and macrophage cell types in the liver and helps protect against tissue fibrosis.

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Care in the Community – How Biofilms Improve Bacterial Survival
Care in the Community – How Biofilms Improve Bacterial Survival
Article

A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.

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Liver Spheroids:  A Major Step Towards Meaningful In Vitro Testing for Human Hepatotoxicity Potential
Liver Spheroids: A Major Step Towards Meaningful In Vitro Testing for Human Hepatotoxicity Potential
Article

The development of new in vitro models to replace in vivo testing has already proven quite successful for certain targets. Among these are models of the immune system and human skin, while in vitro cardiac arrhythmia models are poised to emerge in the near future. Despite this clear progress, an efficient model for liver organ toxicity testing still remains elusive.

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Antigenic Drift vs Antigenic Shift
Antigenic Drift vs Antigenic Shift
Article

As part of the host-pathogen arms race, viruses are continually evolving to evade the host immune response, be it from previous infection or immunity acquired through vaccination. Here we take a look at the processes of antigenic drift and antigenic shift.

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Through the Looking Glass of Single Cell Proteomics
Through the Looking Glass of Single Cell Proteomics
Article

To pick apart the differences between individual cells in complex multicellular organisms, we need to look at cells one-by-one. This article takes a look at how several scientists in North America are using single cell proteomics (SCP) technologies to discern disease pathogenesis and enhance directed stem-cell differentiation.

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Understanding the Lytic Cycle – What Are the Steps?
Understanding the Lytic Cycle – What Are the Steps?
Article

Bacteriophage (phage) are viruses that specifically infect bacteria. They have a two-phase lifecycle, residing in a dormant state within the host genome (lysogenic cycle) or hijacking the host cellular machinery for their own replication (lytic cycle). Here we will explore the important steps of the lytic cycle.

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Chemical Snapshots and Molecular Maps with Mass Spec Imaging
Chemical Snapshots and Molecular Maps with Mass Spec Imaging
Article

Mass spectrometry imaging (MSI) is a powerful tool increasingly being used in many fields including cancer research, biomarker discovery and drug development. This article explains why MSI is the technique of choice in many labs, discusses its use in research, and covers how some inherent challenges are being addressed.

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