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Answer the challenges of CDS Data integrity - Sterling Pharma Solutions Ltd

Webinar

Data integrity continues to be a hot topic for the regulatory agencies in the pharmaceutical industry.

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Advances in Cell Microscopy

List

Since the earliest microscopy efforts in the 1600s, cell imaging has significantly modernized and become a ubiquitous tool in cell biology laboratories. Here, we cover five key advances in cell microscopy to help you understand how the field is progressing.

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What Are Totipotent Stem Cells?

Article

Defining stem cells is important in research and in many fields where they are being used, such as in regenerative medicine and drug discovery. This article focuses on totipotent stem cells, the most potent of all stem cells, and answers fundamental questions such as: What are totipotent stem cells? Where can they be found? Can totipotent stem cells be induced artificially?

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World’s First Reported Spontaneous Clearance of HIV, Without Treatment

News

In 1981, a patient from Sydney was transfused with a weakened form of HIV-1 when he received a blood transfusion following a motorbike accident. After controlling his infection for more than 30 years, he appears to have cleared his infection altogether – without therapy.

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Two Molecules "Awaken" Brand New Genome
News

Giraldez and his research team at Yale found that two specific factors are needed to activate DNA in the newly formed genome.

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Targeting Cell Membrane Proteins to Combat Drug Resistance
News

Certain membrane proteins specialize in transporting molecules out of cells – a problem for the efficacy of cancer medication and antibiotics. Now a team has investigated the transport mechanism of a bacterial membrane protein using an artificially produced antibody fragment.

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Cartilage Ear 3D-printed Without Scaffolding
News

A new approach to bioprinting has been demonstrated in a study that successfully 3D-printed biological tissues without scaffolds using "ink" made up of only stem cells.

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Addressing Gender Bias – “It Is Time to End the Tradition in Science of All-Male Speaking Panels”
Article

Francis S. Collins, M.D., Ph.D. Director of the National Institutes of Health, has recently directly addressed the issue of underrepresented groups in science: "Too often, women and members of other groups underrepresented in science are conspicuously missing in the marquee speaking slots at scientific meetings and other high-level conferences.”

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What Do We Need? Good Vaccine Design! When Do We Need It? Now!
Article

The infectious agents that continually assault our bodies are many and diverse. Even just a few decades ago, diseases such as smallpox and typhoid were killing millions every year and some still are. Thankfully for us, at least for some diseases, this picture has changed, and the development of vaccines has played a not insignificant role in this achievement.

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The Evolution of Proteomics - Professor Alexander Makarov
Article

In this instalment of The Evolution of Proteomics, we speak with Dr Alexander Makarov, Director of Research in Life Sciences Mass Spectrometry (MS) at Thermo Scientific, and world-renowned inventor of the Orbitrap mass analyzer technology.

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The Give and Take Relationship of XL-MS and Cryo-EM
Article

Structural biology has recently observed the marrying of two remarkably complimentary techniques for the study of protein structure and interaction: cross-linking mass spectrometry (XL-MS) and the Nobel prize winning cryogenic electron microscopy (cryo-EM).

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The Evolution of Proteomics - Dr Gary Kruppa
Article

In this instalment of The Evolution of Proteomics, Gary Kruppa, Vice President of Proteomics, Bruker Daltonics Inc., discusses the recent technological advances that are driving MS-based plasma proteomics for biomarker discovery and beyond.

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MeTooSTEM: A Mission to End Sexual Harassment in STEM
Article

In the wake of the "Me Too" (or #MeToo) movement, a spotlight has been cast on an additional obstacle that deters many individuals, particularly women, from working in STEM – the astonishingly high incidence of sexual harassment. In this article, we look at the extent of the issue and speak with some of the women that are working tirelessly to combat sexual harassment in STEM through a variety of organizations.

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