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Application Notes

 
Maintaining the Health and Viability of Cells
Application Note

Cell culture can be a challenging process because cells are influenced by many factors including how they are physically handled and the labware used to seed and feed cultures.

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Improve Recovery of Critical Protein Samples
Application Note

Protein loss during sample preparation can be an obstacle to reliable product quantitation in all biopharmaceutical settings. Samples are often prepared from feedstocks containing insoluble particles and therefore require a solid-liquid separation before analysis to protect analytical instruments.

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Collaboration Delivers Pharma Efficiencies, Data Compliance and Weighing Excellence
Application Note

Time is a precious commodity and with ever-increasing regulatory scrutiny, pharmaceutical laboratories are always on the lookout for simple solutions to make their routine tasks easier. Here, we speak with experts to find out how they helping scientists weigh samples in the most efficient yet trusted way to date.

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Best Practices for Pipetting 3D Cell Culture Hydrogels
Application Note

Three-dimensional (3D) cell cultures are of increasing interest in research areas such as stem-cell based therapies and drug discovery. However, preparing 3D cell cultures can be difficult, and poor pipetting technique may lead to high variation in 3D cell culture experiments.

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Rapid Mammalian Cell Harvest Without Centrifugation for Antibody Purification
Application Note

Download this app note to discover a novel system that enables rapid clarification of mammalian cell cultures without the need for centrifugation and has no impact on product quality.

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Integrating Laboratory Equipment Into Computerized Systems
Application Note

Laboratory information management systems (LIMS) are becoming increasingly important in GMP-regulated environments in order to ensure data integrity and faster working practices.

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Multiomic Profiling of the Immune System at Single-Cell Resolution
Application Note

Traditional methods of immune surveillance allow researchers to interrogate one data type at a time, leaving them with an incomplete understanding of the immune response. In order to characterize the immune response, the ability to phenotype individual cells with multiple parameters and at massive scale is necessary.

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Interrogate the SARS-CoV-2 Genome To Get More Answers
Application Note

Studying the SARS-CoV-2 genome can provide valuable insights into its evolution and transmission, as well as aiding surveillance and vaccine development efforts to help control the COVID-19 pandemic. Download this app note to discover an RNA sequencing approach that can accurately identify low copy number viral pathogens.

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High-Performance CQA Analysis in Biopharma
Application Note

Download this application compendium to discover an ultra-high performance liquid chromatography approach for refined charge variant analysis of mAbs, elevated mAb aggregate analysis and HIC analysis of drug-to-antibody ratio with high salt concentrations.

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Cell-Free Protein Expression Using Twist Gene Fragments
Application Note

A cornerstone of synthetic biology is designing DNA sequences and testing the characteristics and functions of the resultant proteins. Traditional in vivo protein expression workflows can be time-intensive and laborious, and they can fail if the protein is toxic to the host cells.

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