Latest App Notes & Case Studies
App Note / Case Study
Sequencing the Unsequenceable
Download this app note to discover a solution that allows for the sequencing of challenging samples like FFPE and how this can be integrated into automated workflows.
App Note / Case Study
Capture-Based SNP Genotyping With Twist Target Enrichment Panels
In the past two decades, genotyping arrays have been instrumental in the large-scale characterization of single nucleotide polymorphisms (SNPs) and the genetic makeup of individuals. Targeted sequencing has yet to fully replace microarrays due to barriers associated with performance at scale.
App Note / Case Study
Automated Nucleic Acid Extraction and RT-PCR Set-Ups for SARS-CoV-2 Testing
To prevent new infections in China once the number of cases fell, all nationals returning from other countries were tested. This process required rapid testing and automation of the sample preparation process. In order to meet these requirements, scientists have exploited automated pipetting solutions. Download this app note to discover tips on how to automate the testing of suspected COVID-19 positive cases.
App Note / Case Study
Achieve Robust Quantification of Antibody-Dependent Cellular Phagocytosis
Download this app note to discover a high-throughput, multiplex assay that can profile large libraries of mAbs for their effects on antibody-dependent cellular phagocytosis in minimal time.
App Note / Case Study
COVID-19: Automated Solutions To Meet Testing and Sample Handling Requirements
When COVID-19 arrived very few people had anticipated the impact a pandemic would have on the global population and the life sciences industry. Many laboratories are archiving positive COVID-19 samples for future research. Access this app note to discover the uses and advantages of automated storage.
App Note / Case Study
How To Beat Bias in Directed Evolution of Biocatalysts
Because of problems in common PCR-based mutagenesis techniques, there is an urgent need to develop efficient screening and selection tools for biocatalyst improvement. Download this app note to discover a novel approach using solid-phase synthesis of oligonucleotides
App Note / Case Study
Effectiveness of CRISPR-Cas9 Using Pools of Synthetic cRNAs in Screening Experiments
Download this app note to discover an example that shows pooling crRNAs to the same gene target provides robust functional knockout and reveal ways to ensure crRNA pools work successfully in phenotypic screening.
App Note / Case Study
Studying the Molecular Mechanism of Viral Replication in Real Time
Viruses are obligate intracellular pathogens that can infect all living organisms. A clear understanding of host–virus interactions is crucial to uncover the molecular mechanisms underpinning infection and to enable the development of new treatments.
App Note / Case Study
Illuminating the Role of the Adaptive Immune Response in Neurodegeneration
Download this research snapshot to discover how immune repertoire changes in patients with age-related neurodegeneration and how adaptive immune cells are involved in these neurodegenerative diseases.
App Note / Case Study
A Simple Way To Set Up MALDI Imaging Measurements
This technique couples the molecular depth from mass spectrometric detection with the ability to spatially view analytes on a cellular scale, similar to microscopy, enabling users to investigate samples to new depths.
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