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Latest App Notes & Case Studies

mRNA Strand
App Note / Case Study

High-Resolution mRNA Poly(A) Tail Analysis With CGE-UV

This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.
Cell Structure
App Note / Case Study

Large-Scale Expansion of PSCs to Support Cell Therapy Manufacturing

This application note introduces a suspension medium for use in the production of pluripotent stem cells (PSCs) for allogeneic therapies, enabling a seamless transition from research to clinical settings.
Sequencing
App Note / Case Study

Automate Assembly Cloning Using a Liquid Handling Platform

This application note presents a case study where a manual cloning approach was adapted with an automated platform to expedite experiments on 96-well and 384-well plates.
AKTA System
App Note / Case Study

Single-Use Technology Designed for Small Batches in Gene Therapy Manufacturing

But how do you purify small volumes for preclinical and clinical studies without losing too much to processing or leaving capacity unused?
Screen Single Cells in Their Own Microenvironment
App Note / Case Study

Screen Single Cells in Their Own Microenvironment

This app note highlights a uniquely protective environment to support cell viability and integrity during incubation and shield cells against shear stress during subsequent analysis.

Detecting Coding Genes
App Note / Case Study

Streamlined RNA Capture for Gene Expression and Novel Fusions

This application note presents capture sequencing using a novel RNA exome panel as a powerful approach to specifically target the transcriptome to profile gene expression and discover novel fusion genes.
App Note / Case Study

Streamlined Detection and Characterization of Mitochondrial Toxicants

This app note highlights an assay that enables streamlined, sensitive detection and characterization of mitochondrial toxicants.
A Framework for Successful Cell Line Development
App Note / Case Study

A Framework for Successful Cell Line Development

These materials highlight the use of single cell dispensers that enhance efficiency and predictability, improving workflow robustness to support safe and cost-effective biopharmaceutical manufacturing.
PCR Test
App Note / Case Study

Low-Noise PCR Cyclers for an Optimized Lab

This application note evaluates the noise generation of PCR thermal cyclers in varying operational states to assess how different instruments affect background noise levels.
Enabling Custom Oligo Manufacturing
App Note / Case Study

Enabling Custom Oligo Manufacturing

Oligonucleotide therapeutics (OTs) show great promise in the field of personalized medicine as a method of targeting undruggable proteins.
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