Analyzing Biological Samples
Application Note Feb 22, 2012
Tecan’s new patent pending Gas Control Module (GCM) is an innovative solution for cell-based experiments, offering rigorous environmental control within the detection chamber. The pH of cell culture media is typically maintained by a bicarbonate buffer system, using precise control of atmospheric CO2 partial pressure to stabilize the buffer system. Common cell culture incubators are therefore equipped with sensor-based CO2 controls, maintaining a defined atmospheric CO2 level (ranging from 3 to 10 %) to avoid pH shifts which would prevent proliferation or cause cell death.