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Cell Painting for Phenotypic Screening

Cell Painting for Phenotypic Screening content piece image

Cell painting is a powerful phenotypic screening method used to gain a deeper understanding of the effects of chemical and genetic perturbagens on cells. However, implementation of cell painting can come with challenges such as choosing a cell model and labeling reagents, optimizing instrumentation and making sense of the thousands of features that are extracted during data analysis.

Download this app note to discover how to: 

  • Set up optimal imaging parameters and see the effect of different acquisition modes on compound clustering
  • Extract and analyze more than 5700 cellular features
  • Visualize multidimensional data using the Signals™ Screening analysis platform