Cell Painting for Phenotypic Screening

Cell painting is a powerful phenotypic screening method used to gain a deeper understanding of the effects of chemical and genetic perturbagens on cells. However, implementation of cell painting can come with challenges such as choosing a cell model and labeling reagents, optimizing instrumentation and making sense of the thousands of features that are extracted during data analysis.

Download this app note to discover how to: 

• Set up optimal imaging parameters and see the effect of different acquisition modes on compound clustering
• Extract and analyze more than 5700 cellular features
• Visualize multidimensional data using the Signals™ Screening analysis platform