Investigation of Cell Migration using a High Density Cell Exclusion Assay and Automated Microplate Imager

Cell migration, the movement of cells from one location to another, can be the result of complex biological or environmental signaling events. The migration of cells is known to occur during a vast array of both normal biological processes such as the development of an organism, immune response and wound healing or marking pathological events such as cancer metastasis, cardiovascular disease and arthritis1 . The need to better understand the process of cell migration has led to the development of improved methods of investigation including culturing methods, live cell trackers and detection methods. Improvements in both the investigative methods and throughput technologies will allow for rapid expansion of investigation in the area of cell migration research.