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Understanding the Lytic Cycle – What Are the Steps?
Article

Bacteriophage (phage) are viruses that specifically infect bacteria. They have a two-phase lifecycle, residing in a dormant state within the host genome (lysogenic cycle) or hijacking the host cellular machinery for their own replication (lytic cycle). Here we will explore the important steps of the lytic cycle.

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Chemical Snapshots and Molecular Maps with Mass Spec Imaging
Article

Mass spectrometry imaging (MSI) is a powerful tool increasingly being used in many fields including cancer research, biomarker discovery and drug development. This article explains why MSI is the technique of choice in many labs, discusses its use in research, and covers how some inherent challenges are being addressed.

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Three Ways to Turn Life Science Suppliers into Partners
Article

A growing number of life science businesses are turning to greater supply chain collaboration for benefits like accelerated time to market, improved quality, reduced risk and more rapid and widespread innovation. But while 68% of executives in this industry say active and meaningful engagement with suppliers is essential to success, far too many, over a third, struggle to implement it.

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Host Cell Protein Analysis in Biopharma
Article

Presence of host cell protein (HCP) contaminants in the final product, even at very low levels, may elicit unpredictable and serious immunogenic response in humans. The accurate detection, identification and quantification of HCPs during biotherapeutic development is thus critical in ensuring patient safety, and is a regulatory requirement.

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Lytic vs Lysogenic – Understanding Bacteriophage Life Cycles
Article

Bacteriophage (phage) are obligate intracellular viruses that specifically infect bacteria. Here we take an overview of their structure, life-cycle and the role they have played in advancing science and medicine.

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Imaging in Biology: How Many Words are Cell Images Worth?
Article

They say 'a picture is worth a thousand words.' Is this true for cell images?

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Studying the Genome One Cell at a Time
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In 2013, Nature named single-cell sequencing (SCS) as the ‘Method of the Year’, citing its potential to transform the fields of biology and medicine. Now, the technique is bringing to light how genetic information can change between individual cells and facilitating the study of rare cell types. This article explores how these insights have helped scientists understand how diseases like cancer can evolve and spread in humans.

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Why Pharma Is Rethinking Its Data Integration Strategy – the Criticality of Data Integration
Article

The pharma industry is being disrupted in multiple ways. Data has never been more accessible and the speed at which it is flowing has left the industry reeling. Fundamental to the success of these advances is the need to integrate data from diverse sources and leverage predictive analytics to drive informed, real-time decisions. This article explores how pharma can maximize the value of different data types to advance research.

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A Micro-revolution with Giant Benefits
Article

With more and more applications of the microfluidics industry becoming apparent, giving scientists the tools they need has never been more important. This article highlights major industries that benefit from microfluidic technology, and provides insights into how demands for microfluidic components are changing.

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Cancer Cells vs Normal Cells
Article

Cancer is a complex genetic disease that is caused by specific changes to the genes in one cell or group of cells. These changes disrupt normal cell function – specifically affecting how a cell grows and divides. This article outlines some of the key differences between cancer cells and normal cells.

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