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Blog

Why Should Antibodies Be Manufactured Recombinantly?
Blog

Given that bad antibodies are likely to blame for a significant proportion of the reproducibility crisis in science, any efforts to reduce batch-to-batch variability are more than welcome. One company with a plan to help in this area is “Absolute Antibody”, who believe that recombinant antibodies are the way forward. To learn more about making antibodies with recombinant technology, we spoke to Ian Wilkinson, PhD, Chief Scientific Officer.

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Exosomes: Isolation and Investigation
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Exosomes are small vesicles of 30 to 150 nm. To investigate their function there is a need to optimize and standardize the methods employed to isolate exosomes. However, before exploring the different methods, it is worth explaining what makes exosomes so interesting…

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A Microfluidic Approach to Gene Delivery in GMCT
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The development of GMCTs has been halted by issues surrounding the most critical step in their creation, the introduction of new genetic material. Recently, Indee Labs announced the publication of a study illustrating the efficacy of it's GMCT development and manufacturing technology. We spoke with Indee Labs' CEO Ryan Pawell to learn more about the technology and its applications.

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Bringing Balance to the Lab
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It is an undeniable fact that the success of most experiments in R&D and analytical labs hinges on reliable weighing. It should go without say that dependable lab balances are critical. Often little focus is given to such a vital cog in the machine.

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Entering the Antibody Lottery: Tips for Avoiding Dubious Sources
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Having reliable antibodies can make or break your assay. However, sourcing the right antibody for the job can sometimes feel like you’re entering the lottery: there are so many on the market, and often they just don’t live up to what was promised. To learn more about antibody validation and its importance, we got in touch with Anthony Couvillon, PhD, Scientific Marketing Project Manager at Cell Signaling Technology.

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Flow Cytometry in the Clinic
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Flow cytometry is a technique used to count and analyze the size, shape and properties of individual cells. Not just a valuable research tool, flow cytometry is also finding its stride in several clinical areas. Following BD Biosciences’ launch of a new sample preparation instrument, we spoke to Stephen Gunstream, VP and general manager, to get his insights on the role of flow cytometry in the clinic.

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Single-cell DNA Analysis: Driving Dynamic Changes in the Treatment of Cancer
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We recently spoke to Charlie Silver, CEO and Co-Founder of Mission Bio, to learn more about how they are helping researchers profile mutational heterogeneity at the single-cell level.

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Releasing the Handbrake on Exosome Applications
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Despite the great excitement about exosomes and their huge diagnostic and therapeutic potential, the technology needed to advance this work is lacking. We spoke to Jim West, CEO of Clara Biotech, who tells us how his team is working to fill that gap.

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Automated Microfluidic Systems for Gene Editing
Blog

Recently, Oxford Genetics and Sphere Fluidics announced a multi-partner collaboration to expedite the development of automated microfluidic systems for rapid and high-throughput gene editing in mammalian cells. We spoke with Emily Leproust, PhD, CEO of Twist Biosciences, and other collaborators from the partnership to discuss the background of this announcement and the need for automated systems in gene editing.

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Take a Good Book Around
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Our recent social media poll on "book recommendations for scientists" provided an incredible response. We decided to collate this information and give you the perfect excuse to treat yourself to a new read. Enjoy!

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