Professor
at KTH - Royal Institute of Technology
Mathias Uhlén received his PhD at the Royal Institute of Technology (KTH), Stockholm, Sweden in 1984. After a post-doc period at the EMBL in Heidelberg, Germany, he became professor in microbiology at KTH in 1988. His research is focused on protein science, antibody engineering and precision medicine and range from basic research in human and microbial biology to more applied research, including clinical applications in cancer, infectious diseases, cardiovascular diseases, autoimmune diseases and neurobiology. His research has resulted in more than 750 publications. He is a member of several academies and societies, including Royal Swedish Academy of Science, National Academy of Engineering (USA), the Swedish Academy of Engineering Science (IVA) and the European Molecular Biology Organization (EMBO). His group was the first to describe a number of innovations in science including: Affinity-based protein engineering, Real-time sequencing by synthesis, Map of the human proteome (The Human Protein Atlas). The Human Protein Atlas program started by Dr Uhlén in 2003 with the aim to contribute to the holistic understanding of all the proteins encoded from our DNA. The objective of the program is to map all the human proteins in cells, tissues, and organs using integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics, and systems biology. The ultimate aim for the project is a complete understanding of the functions and interactions of all proteins and where in the different cells and tissues they reside. Dr Uhlén was the Founding Director of the SciLifeLab from 2010–2015. This national infrastructure was launched in Stockholm with funding from the Swedish government to allow technology- and data-driven research to be establish as a support for Swedish and European research in life science.
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