CRISPR/Cas9 Genome Editing Products

Cutting edge tools for your genome editing products

Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 is the latest tool in genome editing. A simple yet powerful technology, CRISPR/Cas9 has been adapted from a natural defense mechanism of bacteria and archaea, and can be utilized to target specific sites in the genome. This revolutionary technology allows for the manipulation of specific genes with high specificity and low cell toxicity.

AMSBIO supplies an extensive range of genome editing products to support your research.

How does CRISPR/Cas9 work?

The first step is to design a guide RNA which is complementary to your target gene, and inject into the cell you wish to modify along with a Cas9 protein. Cas9 is a CRISPR-associated endonuclease and acts as a pair of molecular scissors by cutting the target DNA in the specific desired location.

The guide RNA and the Cas9 form a complex, and the Cas9 is guided to the target gene, where the enzyme unwinds the DNA duplex and cleaves both strands specifically at this site. Target recognition can only occur in the presence of a protospacer adjacent motif (PAM) which flanks the target site.

By harnessing the cell’s natural repair mechanisms, we can cause frameshift mutations leading to gene knockout or provide a template for the cell to repair from, leading to targeted insertions. CRISPR/Cas9 technology therefore has the potential to revolutionize the way in which we treat disease, as well as a whole host of other applications, offering numerous advantages over other gene editing methods.

Our Products

NameDatasheetPacksize Order
pCas-Guide10 µg View
pCas-Guide-EF1a-CD4-10 µg View
pCas-Guide-EF1a-GFP-10 µg View
pCas-Scramble10 µg View
pCas-Scramble-EF1a-GFP-10 µg View
pLenti-Cas-Guide10 µg View
pLenti-EF1a-Cas-Guide-10 µg View

NameDatasheetPacksize Order
pAAVS1-Cas9-BSD-DNR-10 µg View
pAAVS1-Cas9-Puro-DNR-10 µg View
pGuide-10 µg View
pGuide-EF1a-GFP-10 µg View
pLenti-Cas9-10 µg View
pLenti-Cas9-IRES-Puro-10 µg View
pLenti-Cas9-P2A-tGFP-10 µg View
pLenti-Guide-Puro-10 µg View
pT7-Cas910 µg View

NamePacksize Order
CAS9-D10A Streptococcus Pyogenes Recombinant Protein500 pmol View
Cas9 NC-NLS Streptococcus Pyogenes Recombinant Protein500 pmol View

NamePacksize Order
pGuide10 µg View
pGuide-EF1a-GFP10 µg View
pLenti-Guide-Puro10 µg View
pT7-Guide-IVT10 µg View

NameDatasheetPacksize Order
AAVS1 Transgene Knockin kit (BSD)-1 kit View
AAVS1 Transgene Knockin kit (EF1a, Puro)1 kit View
AAVS1 Transgene knockin vector kit-1 kit View
pAAVS1-BSD-DNR-10 µg View
pAAVS1-EF1a-BSD-DNR-10 µg View
pAAVS1-EF1a-puro-DNR CRISPR Vector10 µg View
pAAVS1-Puro-DNR-10 µg View
pCas-Guide-AAVS110 µg View

NamePacksize Order
We couldn't find any records.

NamePacksize Order
CRISPRa SAM Vector Kit, CRISPR/Cas9 Gene Activation1 kit View
pCRISPRa-Enhancer Vector, Synergistic Transactivation Domains for CRISPRa10 µg View
pCas-Guide-CRISPRa gene activation vector10 µg View
pCas-Guide-CRISPRa-Scramble10 µg View
pCas-Guide-CRISPRi vector|All-in-one Vector for CRISPR/Cas9 Gene Interference with dCas9-KRAB-MeCP2 and gRNA cloning site.10 µg View
pCas-Guide-CRISPRi-Scramble10 µg View
pCas-Guide-GFP-CRISPRa gene activation vector10 µg View
pCas-Guide-GFP-CRISPRa-Scramble10 µg View
pCas-Guide-GFP-CRISPRi gene interference vector10 µg View
pCas-Guide-GFP-CRISPRi-Scramble10 µg View
pCas-Guide-Puro-CRISPRa gene activation vector10 µg View
pCas-Guide-Puro-CRISPRa-Scramble10 µg View
pCas-Guide-Puro-CRISPRi Vector|All-in-one Vector for CRISPR/Cas9 Gene Interference with Puro selection marker|dCas9-KRAB-MeCP2 and gRNA cloning site.10 µg View

NamePacksize Order
pCas-Guide-Nickase (D10A)10 µg View
pT7-Cas9-Nickase (D10A)10 µg View

Can't find what you're looking for?

We offer a range of CRISPR custom services for your genome editing research