MAPTrix™ - Recombinant Animal Free Extracellular Matrix

• Reproducible and reliable protein coating
• Mix and match motifs to create in vivo-like environment
• Biochemically defined and animal-free
• Coats and adheres to a wide variety of surfaces including glass, plastic and biological surfaces
• Ready to use
• Low cost
• Promotes cell plating efficiency, improved cell morphology and enhanced cell proliferation

MAPTrix^TM bio-mimetics are already used in:

• Stem cell technology,
• Tissue engineering scaffolds,
• Drug delivery,
• Cell surface modification and coating of medical devices.

MAPTrix^TM ECM mimetics have biological activity comparable with its corresponding natural ECM protein and can be used in cell culture application alone or in combination with other products.

To view available bio-mimetics click here alternatively if you know the type of bio-mimetic you are looking for click on the appropriate link below.

• Collagen MAPTrix^TM-C
• Laminin MAPTrix^TM-L
• Fibronectin MAPTrix^TM-F
• Vitronectin MAPTrix^TM-V

The MAPTrix^TM ECM line of products are provided with a guaranteed purity of >90% (SDS-PAGE) with endotoxin levels below 20 EU/mL (LAL assay). Each product is tested for the presence of bacteria, fungi and mycoplasma with biological activity of each product determined in a cell culture assay under serum free conditions.

MAPTrix^TM products are provided as ready-to-use aqueous coating formulations in 1.0 mg, 2.5 mg, 5.0 mg and 10.0 mg sizes.

Our core product (MAPTrix recombinant mussel adhesive protein) is also available without adhesion motifs added; in 2D, Hydrogel and coacervate formats.

Our MAPTrix™ ECM Library is the first commercially available combinatorial synthetic ECM library. It is comprised of hundreds of ECM derived peptide motifs which primarily bind to specific integrins. When combined with high throughput technology, our MAPTrix™ Array based cell culture systems allows one to investigate and/or optimize ECM cues and cellular signaling events which control cellular functions. The information obtained from the cell culture systems can be translated and applied to creating or engineering biomimetic or synthetic microenvironments in order to regulate cell behavior for biomedical applications.

MAPTrix™ Array offers an extensive line of ECM-derived ligands for high throughput cell adhesion assays to identify a cellular adhesion profile against up to 300 cell surface receptor binding peptide motifs.

MAPTrix technology is used in both the MAPTrix^TM ECM coating (2D matrix) and the MAPTrix^TM HyGel kits (3D matrix). The MAPTrix^TM HyGel matrix can be modularly engineered for designed biochemical characteristics by use of either a single MAPTrix^TM ECM motif or a combination of different motifs. To view details on these product ranges, or to compare the advantages of 3D vs 2D cultures click on the appropriate link at the left of this page.