3D Cell Culture: Miniature Dimensions Drive Massive Advances

Listicle

Published: December 14, 2020

Masha Savelieff, PhD

3D Cell Culture: Miniature Dimensions Drive Massive Advances content piece image

Credit: Geoffrey Wahl, Christopher Dravis, National Cancer Institute/Salk Institute

Cell culture has been advancing biological and biomedical research since the first cell line was established in the late 1940s. Cells have mostly been cultured in a two-dimensional (2D) format as a monolayer adhered to a dish or plate well. In the past two decades, however, researchers have begun to switch gears, transitioning away from 2D in favor of three-dimensional (3D) cultures.

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Various 3D cell culture formats
Key research areas that have harnessed 3D cultures

Meet the Author

Masha Savelieff, PhD

Masha Savelieff holds a PhD in chemistry from the University of Illinois. She completed postdoctoral training in Alzheimer’s disease, cancer research and metabolic disease at the University of Michigan.