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Assessing Kinetics in Drug Discovery

Assessing Kinetics in Drug Discovery content piece image

One of the most important factors determining the success of drug discovery is in vivo drug kinetics. This refers to the binding dynamics of a drug to its target including association and dissociation time which affect drug residence time in the body. Drug kinetics are often deprioritized as companies focus more on optimizing target-binding affinity and selectivity. This is despite increasing evidence that kinetic parameters may have a stronger correlation to drug efficacy than affinity parameters.  

Download this listicle to learn more about:

  • The importance of kinetics
  • Experimental techniques
  • Computational modeling tools